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蓝宇，男，1981年生，重庆大学化学化工学院教授\特聘研究员\博士生导师，研究方向为有机化学理论和理论有机化学。蓝宇2003年北京大学化学与分子工程学院获得学士学位，同年继续在北京大学化学与分子工程学院硕博连读，从师于中国科学院院士吴云东教授，专攻理论有机化学，2008年获得理学博士学位。蓝宇2009年至2012年在美国加州大学洛杉矶分校（University of California, Los Angles）从事博士后科研工作，从师于美国科学院院士，K. N. Houk教授，继续研究理论有机化学。2012年4月以“青年百人计划”特聘研究员加入重庆大学化工学院工作，并于2016年9月转入终身制。在独立工作期间，本人以通讯作者身份在包括Accounts Chem. Res.（1篇，IF = 20.27）、J. Am. Chem. Soc.（7篇，IF = 13.86）、Angew. Chem. Int. Ed.（10篇，IF = 11.99）、Nature Commun.（3篇，IF = 12.12）、Chem. Sci.（3篇，IF = 8.67）、ACS Catal.（6篇，IF = 10.61）、Sci. Adv.（1篇）等期刊发表科研论文共计90余篇（含已接收），通讯作者论文累计被他人正面引用达1500余次，全部论文累计被引用达2500余次，目前蓝宇H因子为29。蓝宇博士的Research ID是A-8146-2016（http://www.researcherid.com/rid/A-8146-2016）。蓝宇博士曾经或正在主持国家自然科学基金面上项目2项、青年项目1项。蓝宇博士荣获“2016年中国化学会青年化学奖”。此外，蓝宇还荣获“2015年中国化学会-物理有机化学新人奖”。截止2018年3月，蓝宇博士在学术会议上作邀请报告14次，受邀在高校及科研院所作学术报告31次。
联系方式
(Email) lanyu@cqu.edu.cn
研究方向
主要研究领域为有机化学、金属有机化学、理论有机化学、计算化学，包括但不限于
1. 金属有机化学反应的机理研究，碳氢键活化、碳碳键活化以及交叉偶联反应；
2. 金属有机化学及配体的理论研究与设计，不对称催化反应的理论研究；
3. 酶催化化学反应机理研究；
4. 周环反应的机理研究；
5. 新型碳材料化学修饰的理论研究。
代表性论文、专著和专利
（一）通讯作者论文
(91) “Aryne Trifunctionalization Enabled by 3-Silylaryne as 1,2-Benzdiyne Equivalent” Lv, C.; Wan, C.; Liu, S.; Lan, Y.*; Li, Y.*Org. Lett. 2018, 20, Accepted. (DOI: )
(90) “Counterion Effect and Directing Group Effect in Rh-Mediated C-H Bond Activation Processes: A Theoretical Study” Luo, Y.; Liu, S.; Xu, D.; Qu, L.-B.; Luo, X.*; Bai, R.*; Lan, Y.* J. Organomet. Chem. 2018, 862, ASAP. (DOI: 10.1016/j.jorganchem.2018.03.016)
(89) “Mechanistic Insight Into Cobalt-Catalyzed Stereodivergent Semihydrogenation of Alkynes: The Story of Selectivity Control” Qi, X.; Liu, X.; Qu, L.-B.; Liu, Q.*; Lan, Y.* J. Catal. 2018, 361, Accepted. (DOI: )
(88) “Theoretical insight into phosphoric acid-catalyzed asymmetric conjugate addition of indolizines to α,β-unsaturated ketones” Chen, H.; Zhu, L.; Zhong, K.; Yue, X.; Qu, L.-B.; Bai, R.*; Lan, Y.* Chin. Chem. Lett. 2018, 29, Accepted. (DOI: )
(87) “Mechanism of phosphinecatalyzed allene coupling reactions: advances in theoretical investigations” Cui, C.-X.; Shan, C.; Zhang, Y.-P.; Chen, X.-L.; Qu, L.-B.*; Lan, Y.* Chem. Asian J. 2018, 13, ASAP. (DOI: 10.1002/asia.201800146)
(86) “Ni-Catalyzed C–F Bond Functionalization of Unactivated Aryl Fluorides and Corresponding Coupling with Oxazoles” Yin, Y.; Yue, X.; Zhong, Q.; Jiang, H.; Bai, R.*; Lan, Y.*; Zhang, H. Adv. Synth. Catal. 2018, 360, ASAP. (DOI: 10.1002/adsc.201701506)
(85) “C–H bond Cleavage Occurring on a Rh(V) Intermediate: a Theoretical Study of Rh-Catalyzed Arene Azidation” Liu, S.; Qi, X.; Qu, L.-B.; Bai, R.*; Lan, Y.* Catal. Sci. Tech. 2018, 8, ASAP. (DOI: 10.1039/c7cy02367g)
(84) “Regioselective Palladium-Catalyzed C H Bond Trifluoroethylation of Indoles: Exploration and Mechanistic Insight” Zhang, H.; Wang, H.-Y.; Luo, Y.; Chen, C.; Cao, Y.; Chen, P.; Guo, Y.-L.; Lan, Y.*; Liu, G.* ACS Catal. 2018, 8, 2173-2180. (DOI: 10.1021/acscatal.7b03220)
(83) “Palladium-Catalyzed Intermolecular Ditrifluoromethoxylation of Unactivated Alkenes: CF3O Palladation Initiated by Pd(IV)” Chen, C.; Luo, Y.; Fu, L.; Chen, P.; Lan, Y.*; Liu, G. J. Am. Chem. Soc. 2018, 140, 1207-1210. (DOI: 10.1021/jacs.7b11470)
(82) “Insights of Disilylation and Distannation: Sequence Influence and Ligand/Steric Effect in Pd-Catalyzed Difunctionalization of Carbenes” Yue, X.; Shan, C.; Qi, X.; Luo, X.; Zhu, L.; Zhang, T.; Li, Y.; Li, Y.; Bai, R.*; Lan, Y.* Dalton Trans. 2017, 46, 1819-1826. (DOI: 10.1039/C7DT04084A)
(81) “Ruthenium(II)-catalyzed C-H Difluoromethylation of Ketoxime: Tuning the Regioselectivity from meta to para Position” Yuan, C.; Zhu, L.; Zeng, R.; Lan, Y.*; Zhao, Y.* Angew. Chem. Int. Ed. 2018, 57, 1277-1281. (DOI: 10.1002/anie.201711221)
(80) “On the Mechanism of Copper-Catalyzed Oxytrifluoromethylation of Allylamines with CO2: A Computational Study” Zhu, L.; Ye, J.-H.; Duan, M.; Qi, X.; Yu, D.-G.*; Bai, R.*; Lan, Y.* Org. Chem. Front. 2017, 4, 633-639. (DOI: 10.1039/C7QO00838D)
(79) “Ni(I)–Ni(III) vs Ni(II)–Ni(IV): Mechanistic Study of Ni-catalyzed Alkylation of Benzamides with Alkyl Halides” Li, Y.; Zou, L.; Bai, R.*; Lan, Y.* Org. Chem. Front. 2017, 4, 615-622. (DOI: 10.1039/C7QO00850C)
(78) “C(sp2)-C(sp2) Reductive Elimination from Well-Defined Diarylgold(III) Complexes” Kang, K.; Liu, S.; Xu, T.; Wang, D.; Leng, X.; Bai, R.; Lan, Y.*; Shen, Q.* Organometallics 2017, 35, 4727-4740. (DOI: 10.1021/acs.organomet.7b00588)
(77) “Reactivity and regioselectivity in Diels–Alder reactions of anion encapsulated fullerenes” Cui, C.-X.; Zhang, Z.-P.; Zhu, L.; Qu, L.-B.; Zhang, Y.-P.; Lan, Y.* Phys. Chem. Chem. Phys. 2017, 42, 30393-30401. (DOI: 10.1039/C7CP06365B)
(76) “Mechanism of Rhodium-Catalyzed C−H Functionalization: Advances in Theoretical Investigation” Qi, X.; Li, Y.; Bai, R.; Lan, Y.* Acc. Chem. Res. 2017, 50, 2799-2808. (DOI: 10.1021/acs.accounts.7b00400)
(75) “Radical Trifluoromethylative Dearomatization of Indoles and Furans with CO2” Ye. J.-H.; Zhu, L.; Yan, S.-S.; Miao, M.; Zhang, X.-C.; Zhou, W.-J.; Li, J.; Lan, Y.*; Yu, D.-G.* ACS Catal. 2017, 7, 8324-8330. (DOI: 10.1021/acscatal.7b02533)
(74) “Rhodium/Copper Cocatalyzed Highly trans-Selective 1,2- Diheteroarylation of Alkynes with Azoles via C−H Addition/Oxidative Cross-Coupling: A Combined Experimental and Theoretical Study” Tan, G.; Zhu, L.; Liao, X.; Lan, Y.*; You, J.* J. Am. Chem. Soc. 2017,139, 15724-15737. (DOI: 10.1021/jacs.7b07242)
(73) “Nine-Membered Benzofuran-Fused Heterocycles: Enantioselective Synthesis by Pd-Catalysis and Rearrangement via Transannular Bond Formation” Rong, Z.-Q.; Yang, L.-C.; Liu, S.; Yu, Z.; Wang, Y.-N.; Tan, Z. Y.; Huang, R.-Z.; Lan, Y.*; Zhao, Y.* J. Am. Chem. Soc.2017, 139, 15304-15307. (DOI: 10.1021/jacs.7b09161)
(72) “Mechanistic Study on the Fluoride-induced Activation of Kobayashi Precursor: pseudo-SN2 Pathway via a PentaCoordinated Silicon ate-Complex” Liu, S.; Li, Y.*; Lan, Y.* Eur. J. Org. Chem. 2017, 42, 6349-6353. (DOI: 10.1002/ejoc.201701249)
(71) “Cp*CoIII-Catalyzed Branch-Selective Hydroarylation of Alkynes via C−H Activation: Efficient Access to α-gem-Vinylindoles” Zhou, X.; Luo, Y.; Kong, L.; Xu, Y.; Zheng, G.; Lan, Y.*; Li, X.* ACS Catal. 2017, 7, 7296-7304. (DOI: 10.1021/acscatal.7b02248)
(70) “Bond dissociation energy controlled σ-bond metathesis in alkaline-earth-metal hydride catalyzed dehydrocoupling of amines and boranes: a theoretical study” Xu, D.; Shan, C.; Li, Y.; Qi, X.; Luo, X.*; Bai, R.*; Lan, Y.* Inorg. Chem. Front. 2017, 4, 1813. (DOI: 10.1039/c7qi00459a)
(69) “From Mechanistic Study to Chiral Catalyst Optimization: Theoretical Insight into Binaphthophosphepine-catalyzed Asymmetric Intramolecular [3+2] Cycloaddition” Duan, M.; Zhu, L.; Qi, X.; Yu, Z.; Li, Y.; Bai, R.*; Lan, Y.* Sci. Rep. 2017, 7, 7619. ( DOI:10.1038/s41598-017-07863-9)
(68) “Catalyst-controlled regioselectivity in phosphine catalysis: the synthesis of spirocyclic benzofuranones via regiodivergent [3+2] annulations of aurones and an allenoate” Ni, H.; Yu, Z.; Yao, W.; Lan, Y.*; Ullah, N.*; Lu, Y.* Chem. Sci. 2017, 8, 5699-5704. (DOI: 10.1039/c7sc02176c)
(67) “Mechanistic insights into copper-catalyzed trifluoromethylation of aryl boronic acids: a theretical study.” He, X.; Shan, C.; Qi, X.*; Bai, R.*; Lan, Y.* Sci. Sin. Chem. 2017, 47, 859-864. (DOI: 10.1360/N032017-00056)
(66) “Ir(III)/Ir(V) or Ir(I)/Ir(III) Catalytic Cycle? Steric-Effect-Controlled Mechanism for the para-C−H Borylation of Arenes” Zhu, L.; Qi, X.; Li, Y.; Duan, M.; Zou, L.; Bai, R.*; Lan, Y.* Organometallics 2017, 36, 2107-2115. (DOI: 10.1021/acs.organomet.7b00151)
(65) “Chiral phosphine-mediated intramolecular [3+2] annulation: enhanced enantioselectivity by achiral Br➢nsted acid” Yao, W.; Yu, Z.; Wen, S.; Ni, H.; Ullah, N.*; Lan, Y.*; Lu, Y.* Chem. Sci. 2017, 8, 5196-5200. (DOI: 10.1039/c7sc00952f)
(64) “Enantioselective alkynylation of N-sulfonyl a-ketiminoesters via a Friedel–Crafts alkylation strategy” Liu, R.-R.; Zhu, L.; Hu, J.-P.; Lu, C.-J.; Gao, J.-R.; Lan, Y.*; Jia, Y.-X.* Chem. Commun. 2016, 52, 5890-5893. (DOI: 10.1039/c7cc01015j)
(63) “Bioinspired Total Synthesis of Homodimericin” A Huang, J.; Gu, Y.; Guo, K.; Zhu, L.; Lan, Y.*; Gong, J.*; Yang, Z.* Angew. Chem. Int. Ed. 2017, 56, 7890-7894. ( DOI: 10.1002/anie.201702768)
(62) “Mechanism, Regio-, and Diastereoselectivity of Rh(III)-Catalyzed Cyclization Reactions of N Arylnitrones with Alkynes: A Density Functional Theory Study” Li, Y.; Shan, C.; Yang, Y.-F.; Shi, F.; Qi, X.; Houk, K. N.*; Lan, Y.* J. Phys. Chem. A 2017, 121, 4496-4504. ( DOI: 10.1021/acs.jpca.7b01020)
(61) “Bioinspired Asymmetric Synthesis of Hispidanin” A Li, F.; Tu, Q.; Chen, S.; Zhu, L.; Lan, Y.*; Gong, J.*; Yang, Z.* Angew. Chem. Int. Ed. 2017, 56, 5844-5848. (DOI: 0.1002/anie.201700838)
(60) “C−O Functionalization of α Oxyboronates: A Deoxygenative gemDiborylation and gem-Silylborylation of Aldehydes and Ketones” Wang, L.; Zhang, T.; Sun, W.; He, Z.; Xia, C.; Lan, Y.*; Liu, C.* J. Am. Chem. Soc. 2017, 139, 5257-5264. (DOI: 10.1021/jacs.7b02518)
(59) “Mononuclear or Dinuclear? Mechanistic Study of the ZincCatalyzed Oxidative Coupling of Aldehydes and Acetylenes” Yue, X.; Qi, X.; Bai, R.; Lei, A.*; Lan, Y.* Chem. Eur. J. 2017, 23, 6419-6425. (DOI: 10.1002/chem.201700733)
(58) “Mechanism of Alkaline Earth Metal Catalyzed Hydroboration of Carbodiimides: A Theoretical Study” Xu, D.; Shan, C.; Bai, R.*; Lan, Y.* Chin. J. Org. Chem. 2017, 37, 1231-1236. (DOI: 10.6023/cjoc201701033)
(57) “Regioselective a-Addition of Deconjugated Butenolides: Enantioselective Synthesis of Dihydrocoumarins” Wu, B.; Yu, Z.; Gao, X.; Lan, Y.*; Zhou, Y.* Angew. Chem. Int. Ed. 2017, 56, 4006-4010. (DOI:10.1002/anIe.201700437)
(56) “Stabilization of Two Radicals with One Metal: A Stepwise Coupling Model for Copper-Catalyzed Radical–Radical Cross-Coupling” Qi, X.; Zhu, L.; Bai, R.*; Lan, Y.* Sci. Rep. 2017, 7, 43579. (DOI: 10.1038/srep43579)
(55) “Thiolate–palladium(IV) or sulfonium–palladate(0)? A theoretical study on the mechanism of palladium-catalyzed C–S bond formation reactions” Xu, D.; Qi, X.; Duan, M.; Yu, Z.; Zhu, L.; Shan, C.; Yue, X.; Bai, R.*; Lan, Y.* Org. Chem. Front. 2017, 4, 943-950. (DOI: 10.1039/c6qo00841k)
(54) “Room-Temperature Coupling/Decarboxylation Reaction of α Oxocarboxylates with α Bromoketones: Solvent-Controlled Regioselectivity for 1,2- and 1,3-Diketones” He, Z.; Qi, X.; She, Z.; Zhao, Y.; Li, S.; Tang, J.; Gao, G.*; Lan, Y.*; You, J.* J. Org. Chem. 2017, 82, 1403-1411. (DOI: 10.1021/acs.joc.6b02575)
(53) “Application of Gausian Software in Organic Chemistry Teaching in Senior High School” Li, Y.;* Qi, X.; Lan, Y.* Chin. J. Chem. Edu. 2017, 38(13), 43. (DOI: 10.13884/J.1003-3807hxjy.2016120022)
(52) “Biomimetically inspired asymmetric total synthesis of (+)-19-dehydroxyl arisandilactone” A Han, Y.; Jiang, Y.; Li, Y.; Yu, H.; Tong, B.; Niu, Z.; Zhou, S.; Liu, S.; Lan, Y.;* Chen, J.;* Yang, Z.;* Nat. Commun. 2017, 8, 14233. (DOI: 10.1038/ncomms14233)
(51) “Ligand effect on nickle-catalyzed reductive alkyne-aldehyde coupling reactions: a computational study. ” Luo, X.; Li, Y.; Qi, X.; Zhu, L.; Chen, C.;* Lan, Y.* Sci. Sin. Chem. 2017, 47, 341-349. (DOI:10.1360/N032016-00129)
(50) “Computational Investigation of the Role Played by Rhodium(V) in the Rhodium(III)-Catalyzed ortho-Bromination of Arenes” Zhang, T.; Qi, X.; Liu, S.; Bai, R.; * Liu, C.; * Lan, Y.* Chem.-Eur. J. 2017, 23, 2690-2699. (DOI: 10.1002/chem.201605188)
(49) “Readily Accessible and Highly Efficient Ferrocene-Based AminoPhosphine-Alcohol (f-Amphol) Ligands for Iridium-Catalyzed Asymmetric Hydrogenation of Simple Ketones” Yu, J.; Duan, M.; Wu, W.;Qi, X. ; Xue, P.; Lan, Y.;* Dong, X-Q.;* Zhang, X.;* Chem.-Eur. J. 2017, 23, 970-975. (DOI: 10.1002/chem.201604855)
(48) “C8–H bond activation vs. C2–H bond activation: from naphthyl amines to lactams” Shi, R.; Lu, L.; Xie, H.; Yan, J.; Xu, T.; Zhang, H.; Qi, X.; Lan, Y.*; Lei, A.* Chem. Commun. 2016, 52, 13307. ( DOI: 10.1039/c6cc06358f)
(47) “Mild Acylation of C(sp3)−H and C(sp2)−H Bonds under Redox-Neutral Rh(III) Catalysis” Yu, S.; Li, Y.; Kong, L.; Zhou, X.; Tang, G.; Lan, Y.;* Li, X.* ACS Catal. 2016, 6, 7744-7748. (DOI: 10.1021/acscatal.6b02668)
(46) “Effective Chirality Transfer in [3+2] Reaction between AllenylRhodium and Enal: Mechanistic Study Based on DFT Calculations” Qi, X.; Liu, S.; Zhang, T.; Long, R.; Huang, J.; Gong, J.; Yang, Z.;* Lan, Y.* J. Org. Chem. 2016, 81, 8306-8311. (DOI: 10.1021/acs.joc.6b01429)
(45) “Asymmetric Transfer Hydrogenation of Imines using Alcohol: Efficiency and Selectivity are Influenced by the Hydrogen Donor” Pan, H. J.; Zhang, Y.; Shan, C.; Yu, Z.; Lan, Y.;* Zhao, Y.* Angew. Chem. Int. Ed. 2016, 55, 9615-9619. (DOI:10.1002/anie.201604025)
(44) “Reactivity of Single-Walled Carbon Nanotubes in the Diels–Alder Cycloaddition Reaction: Distortion–Interaction Analysis along the Reaction Pathway” Li, Y.; Osuna, S.; Garcia-Borràs, M.; Qi, X.; Liu, S.; Houk, K. N.;* Lan, Y.* Chem.-Eur. J. 2016, 22, 12819-12824. (DOI: 10.1002/chem.201601799)
(43) “Iridium Catalysts with f Amphox Ligands: Asymmetric Hydrogenation of Simple Ketones” Wu, W.; Liu, S.; Duan, M.; Tan, X.; Chen, C.; Xie, Y.; Lan, Y.;* Dong, X.-Q.; Zhang, X.* Org. Lett. 2016, 18, 2938-2941. (DOI: 10.1021/acs.orglett.6b01290)
(42) “Computational Studies on an Aminomethylation Precursor: (Xantphos)Pd(CH2NBn2)+” Qi, X.; Liu, S.; Lan, Y.* Organometallics 2016, 35, 1582-1585. (DOI: 10.1021/acs.organomet.6b00234)
(41) “Anthranil: An Aminating Reagent Leading to Bifunctionality for Both C(sp3)-H and C(sp2)-H under Rhodium(III) Catalysis” Yu, S.; Tang, G.; Li, Y.; Zhou, X.; Lan, Y.;* Li, X.* Angew. Chem. Int. Ed. 2016, 55, 8696-8700. (DOI: 10.1002/anie.201602224)
(40) “Efficient Synthesis of Dimeric Oxazoles, Piperidines and Tetrahydroisoquinolines from N-Substituted 2-Oxazolones” He, Y.;* Agarwal, P. K.; Kiran, I. N.; Yu, R.; Cao, B.; Zou, C.; Zhou, X.; Xu, H.; Xu, B.; Zhu, L.; Lan, Y.;* Nicolaou, K. C.* Chem.-Eur. J.2016, 22, 7696-7701. (DOI: 10.1002/chem.201601471)
(39) “Regio- and Stereoselective Syntheses of 7-Oxabicyclo[2.2.1]heptanes via a Gold(I)-Catalyzed Cycloisomerization of Alkynediols: Asymmetric Total Synthesis of Farnesiferol C” Gu, Y.-Q.; Zhang, P.-P.; Fu, J.-K.; Liu, S.; Lan, Y.*; Gong, J.-X.*; Yang, Z.* Adv. Synth. Catal. 2016, 358, 1392-1397. (DOI: 10.1002/adsc.201600218)
(38) “Mechanism of Ruthenium-Catalyzed Direct Arylation of C−H Bonds in Aromatic Amides: A Computational Study” Shan, C.; Luo, X.; Qi, X.; Liu, S.; Li, Y.; Lan, Y.* Organometallics 2016, 35, 1440-1445. (DOI: 10.1021/acs.organomet.6b00064)
(37) “Rhodium-Catalyzed Cyclocarbonylation of Ketimines via C−H Bond Activation” Gao, B.; Liu, S.; Lan, Y.*; Huang, H.* Organometallics 2016, 35, 1480-1487. (DOI: 10.1021/acs.organomet.6b00072)
(36) “Mechanism of Rhodium-Catalyzed Formyl Activation: A Computational Study” Luo, X.; Bai, R.; Liu, S.; Shan, C.; Chen, C.;Lan, Y.* J. Org. Chem. 2016, 81, 2320-2326. (DOI: 10.1021/acs.joc.5b02828)
(35) “Mechanism and electronic effect for the synthesis of 6-aroylated phenanthridines: a theoretical study” Xu, T.; Qi, X.; Lan, Y.* Sci. Sin. Chem. 2016, 46, 616-622. (DOI: 10.1360/N032015-00217)
(34) “Rhodium-Catalyzed Hetero-(5+2) Cycloaddition of Vinylaziridines and Alkynes: A Theoretical View of the Mechanism and Chirality Transfer” Zhu, L.; Qi, X.; Lan, Y.* Organometallics 2016, 35, 771-777. (DOI: 10.1021/acs.organomet.6b00007)
(33) “Rhodium(III)-Catalyzed Annulation between N Sulfinyl Ketoimines and Activated Olefins: C−H Activation Assisted by an Oxidizing N−S Bond” Wang, Q.; Li, Y.; Qi, Z.; Xie, F.; Lan, Y.*; Li, X.* ACS Catal. 2016, 6, 1971-1980. (DOI: 10.1021/acscatal.5b02297)
(32) “Gold(I)-Catalyzed Angle Strain Controlled Strategy to Furopyran Derivatives from Propargyl Vinyl Ethers: Insight into the Regioselectivity of Cycloisomerization” Jin, S.; Jiang, C.; Peng, X.; Shan, C.; Cui, S.; Niu, Y.; Liu, Y.; Lan, Y.*; Liu, Y.*; Cheng, M.* Org. Lett. 2016, 18, 680-683. (DOI: 10.1021/acs.orglett.5b03641)
(31) “Mechanism of Synergistic Cu(II)/Cu(I)-Mediated Alkyne Coupling: Dinuclear 1,2-Reductive Elimination after Minimum Energy Crossing Point” Qi, X.; Bai, R.; Zhu, L.; Jin, R.; Lei, A.; Lan, Y.* J. Org. Chem. 2016, 81, 1654-1660. (DOI: 10.1021/acs.joc.5b02797)
(30) “Iron-Catalyzed Decarboxylative (4+1) Cycloadditions: Exploiting the Reactivity of Ambident Iron-Stabilized Intermediates” Wang, Q.; Qi, X.; Lu, L. Q.*; Li, T. R.; Yuan, Z. G.; Zhang, K.; Li, B. J.; Lan, Y.*; Xiao, W. J.* Angew. Chem. Int. Ed. 2016, 55, 2840-2844. (DOI: 10.1002/anie.201510413)
(29) “Regiodivergent Enantioselective γ Additions of Oxazolones to 2,3-Butadienoates Catalyzed by Phosphines: Synthesis of α,α-Disubstituted α Amino Acids and N,O Acetal Derivatives” Wang, T.; Yu, Z.; Hoon, D. L.; Phee, C. Y.; Lan, Y.*; Lu, Y.* J. Am. Chem. Soc. 2016, 138, 265-271. (DOI: 10.1021/jacs.5b10524)
(28) “Mechanism, chemoselectivity and enantioselectivity for the rhodium-catalyzed desymmetric synthesis of hydrobenzofurans: a theoretical study” Yu, Z.; Qi, X.; Li, Y.; Liu, S.; Lan, Y.* Org. Chem. Front. 2016, 3, 209-216. (DOI: 10.1039/c5qo00334b)
(27) “Copper-catalyzed aerobic oxidative coupling: From ketone and diamine to pyrazine” Wu, K.; Huang, Z.; Qi, X.; Li, Y.; Zhang, G.; Liu, C.; Yi, H.; Meng, L.; Bunel, E. E.; Miller, J. T.; Pao, C. W.; Lee, J. F.; Lan, Y.*; Lei, A.* Sci. Adv. 2015, 1, e1500656. (DOI: 10.1126/sciadv.1500656)
(26) “Silver Migration Facilitates Isocyanide-Alkyne [3+2] Cycloaddition Reactions: Combined Experimental and Theoretical Study” Qi, X.; Zhang, H.; Shao, A.; Zhu, L.; Xu, T.; Gao, M.*; Liu, C.*; Lan, Y.* ACS Catal.2015, 5, 6640-6647. ( DOI: 10.1021/acscatal.5b02009)
(25) “Towards a general diastereoselective route to oxabicyclo[3.2.1]octanes via a gold-catalysed cascade reaction” Fu, J.; Gu, Y.; Yuan, H.; Luo, T.; Liu, S.; Lan, Y.*; Gong, J.*; Yang, Z.* Nat. Commun. 2015, 6, 8617. (DOI: 10.1038/ncomms9617)
(24) “Development of a Rhodium(II)-Catalyzed Chemoselective C(sp3)-H Oxygenation” Lin, Y.; Zhu, L.; Lan, Y.*; Rao, Y.* Chem.-Eur. J. 2015, 21, 14937-14942. (DOI: 10.1002/chem.201502140.)
(23) “Diastereoselective Synthesis of Cyclopentanoids: Applications to the Construction of the ABCD Tetracyclic Core of Retigeranic Acid” A Zhang, J.; Wang, X.; Li, S.; Li, D.; Liu, S.; Lan, Y.*; Gong, J.*; Yang, Z.* Chem.-Eur. J. 2015, 21, 12596-12600. (DOI: 10.1002/chem.201502423)
(22) “Distortion–interaction analysis along the reaction pathway to reveal the reactivity of the Alder-ene reaction of enes” Jin, R.; Liu, S.; Lan, Y.* RSC Adv. 2015, 5, 61426-61435. (DOI: 10.1039/c5ra10345b)
(21) “Highly enantioselective construction of tertiary thioethers and alcohols via phosphine-catalyzed asymmetric g-addition reactions of 5H-thiazol-4- ones and 5H-oxazol-4-ones: scope and mechanistic understandings” Wang, T.; Yu, Z.; Hoon, D. L.; Huang, K.-W.;Lan, Y.*; Lu, Y.* Chem. Sci. 2015, 6, 4912-4922. (DOI: 10.1039/c5sc01614b)
(20) “Mechanism and selectivity for zinc-mediated cycloaddition of azides with alkynes: a computational study” Li, Y.; Qi, X.; Lei, Y.; Lan, Y.* RSC Adv. 2015, 5, 49802-49808. (DOI: 10.1039/c5ra02703a)
(19) “The Mechanism of N-O Bond Cleavage in Rhodium-Catalyzed C-H Bond Functionalization of Quinoline N-oxides with Alkynes:A Computational Study” Li, Y.; Liu, S.; Qi, Z.; Qi, X.; Li, X.*; Lan, Y.* Chem.-Eur. J. 2015, 21, 10131-10137. (DOI: 10.1002/chem.201500290)
(18) “Dinuclear versus mononuclear pathways in zinc mediated nucleophilic addition: a combined experimental and DFT study” Qi, X.; Li, Y.; Zhang, G.; Li, Y.; Lei, A.*; Liu, C.*; Lan, Y.* Dalton Trans. 2015, 44, 11165-11171. (DOI: 10.1039/c5dt01366f)
(17) “Tuning radical reactivity using iodine in oxidative C(sp3)–H/C(sp)–H cross-coupling: an easy way toward the synthesis of furans and indolizines” Tang, S.; Liu, K.; Long, Y.; Qi, X.; Lan, Y.*; Lei, A.*Chem. Commun. 2015, 51, 8769-8772. (DOI: 10.1039/c5cc01825k)
(16) “Nickel-Catalyzed Selective Oxidative Radical Cross-Coupling: An Effective Strategy for Inert Csp3−H Functionalization” Liu, D.; Li, Y.; Qi, X.; Liu, C.; Lan, Y.*; Lei, A.* Org. Lett. 2015, 17, 998-1001. (DOI: 10.1021/acs.orglett.5b00104)
(15) “Bimetallic zinc complex–active species in coupling of terminal alkynes with aldehydes via nucleophilic addition/Oppenauer oxidation” Yuan, J.; Wang, J.; Zhang, G.; Liu, C.; Qi, X.; Lan, Y.*; Miller, J. T.; Kropf, A. J.; Bunel, E. E.; Lei, A.* Chem. Commun. 2015, 51, 576-579. (DOI: 10.1039/c4cc08152h)
(14) “Revealing the halide effect on the kinetics of the aerobic oxidation of Cu(I) to Cu(II) ” Deng, Y.; Zhang, G.; Qi, X.; Liu, C.; Miller, J. T.; Kropf, A. J.; Bunel, E. E.; Lan, Y.*; Lei, A.* Chem. Commun. 2015, 51, 318-321. (DOI: 10.1039/c4cc05720a)
(13) “Transition-Metal-Free Formal Decarboxylative Coupling of a-Oxocarboxylates with a-Bromoketones under Neutral Conditions: A Simple Access to 1,3-Diketones” He, Z.; Qi, X.; Li, S.; Zhao, Y.; Gao, G.*; Lan, Y.*; Wu, Y.; Lan, J.; You, J.* Angew. Chem. Int. Ed.2015, 54, 855-859. (DOI: 10.1002/anie.201409361)
(12) “Rhodium-Catalyzed C−H Activation of Phenacyl Ammonium Salts Assisted by an Oxidizing C−N Bond: A Combination of Experimental and Theoretical Studies” Yu, S.; Liu, S.; Lan, Y.*; Wan, B.*; Li, X.* J. Am. Chem. Soc. 2015, 137, 1623-1631. (DOI: 10.1021/ja511796h)
(11) “Transition-Metal-Assisted Radical/Radical Cross-Coupling: A New Strategy to the Oxidative C(sp3)−H/N−H Cross-Coupling” Zhou, L.; Tang, S.; Qi, X.; Lin, C.; Liu, K.; Liu, C.; Lan, Y.*; Lei, A.* Org. Lett. 2014, 16, 3404-3407. (DOI: 10.1021/ol501485f)
(10) “Carbon-Centered Radical Addition to O=C of Amides or Esters as a Route to CO Bond Formations” Liu, D.; Tang, S.; Yi, H.; Liu, C.; Qi, X.; Lan, Y.*; Lei, A.* Chem.-Eur. J. 2014, 20, 15605-15610. (DOI: 10.1002/chem.201404607)
(9) “Chemoselective Carbophilic Addition of a-Diazoesters through Ligand-Controlled Gold Catalysis” Xi, Y.; Su, Y.; Yu, Z.; Dong, B.; McClain, E. J.; Lan, Y.*; Shi, X.* Angew. Chem. Int. Ed. 2014, 53, 9817-9821. (DOI: 10.1002/anie.201404946)
(8) “Visible-Light-Mediated Decarboxylation/Oxidative Amidation of a-Keto Acids with Amines under Mild Reaction Conditions Using O2” Liu, J.; Liu, Q.; Yi, H.; Qin, C.; Bai, R.; Qi, X.; Lan, Y.*; Lei, A.* Angew. Chem. Int. Ed. 2014, 53, 502-506. (DOI: 10.1002/anie.201308614)
(7) “Cu(II)−Cu(I) Synergistic Cooperation to Lead the Alkyne C−H Activation” Bai, R.; Zhang, G.; Yi, H.; Huang, Z.; Qi, X.; Liu, C.; Miller, J. T.; Kropf, A. J.; Bunel, E. E.; Lan, Y.*; Lei, A.* J. Am. Chem. Soc. 2014, 136, 16760-16763. (DOI: 10.1021/ja5097489)
(6) “Asymmetric total synthesis of (-)-lingzhiol via a Rh-catalysed [3+2] cycloaddition” Long, R.; Huang, J.; Shao, W.; Liu, S.; Lan, Y.*; Gong, J.*; Yang, Z.* Nat. Commun. 2014, 5, 5707. (DOI: 10.1038/ncomms6707)
(5) “Theoretical study of the electron-donating effects of thiourea ligands in catalysis” Liu, S.; Lei, Y.; Yang, Z.*; Lan, Y.* J. Mol. Struct. 2014, 1074, 527-533. (DOI:10.1016/j.molstruc.2014.06.034)
(4) “Hexahapto-chromium complexes of graphene: a theoretical study” Liu, S.; Lei, Y.; Li, Y.; Zhang, T.; Wang, H.; Lan, Y.* RSC Adv. 2014, 4, 28640. (DOI: 10.1039/c4ra03702b)
(3) “What Controls Stereoselectivity and Reactivity in the Synthesis of a trans-Decalin with a Quaternary Chiral Center via the Intramolecular Pauson−Khand Reaction: A Theoretical Study” Liu, S.; Shen, H.; Yu, Z.; Shi, L.; Yang, Z.*; Lan, Y.* Organometallics 2014, 33, 6282-6285. (DOI: 10.1021/om500840q )
(2) “Reactivity for the Diels−Alder Reaction of Cumulenes: A Distortion-Interaction Analysis along the Reaction Pathway” Liu, S.; Lei, Y.; Qi, X.; Lan, Y.* J. Phys. Chem. A 2014, 118, 2638-2645. (DOI: 10.1021/jp411914u)
(1) “Mechanism of Rhodium-Catalyzed Carbon−Silicon Bond Cleavage for the Synthesis of Benzosilole Derivatives: A Computational Study” Yu, Z.; Lan, Y.* J. Org. Chem. 2013, 78, 11501-11507. (DOI: 10.1021/jo402070f)
（二）第一作者论文
(8) “Why Nature Eschews the Concerted [2+2+2] Cycloaddition of a Nonconjugated Cyanodiyne. Computational Study of a Pyridine Synthesis Involving an Ene−Diels−Alder−Bimolecular Hydrogen- Transfer Mechanism” Lan, Y.; Danheiser, R. L.*; Houk, K. N.* J. Org. Chem. 2012, 77, 1533-1538. (DOI: 10.1021/jo202424n)
(7) “Theoretical study of Pd(0)-catalyzed carbohalogenation of alkenes: mechanism and origins of reactivities and selectivities in alkyl halide reductive elimination from Pd(II) species” Lan, Y.; Liu, P.; Newman, S. G.; Lautens, M.*; Houk, K. N.* Chem. Sci. 2012, 3, 1987. (DOI: 10.1039/c2sc20103h)
(6) “Computational Methods To Calculate Accurate Activation and Reaction Energies of 1,3-Dipolar Cycloadditions of 24 1,3-Dipoles”Lan, Y.; Zou, L.; Cao, Y.; Houk, K. N.* J. Phys. Chem. A 2011, 115, 13906-13920. (DOI: 10.1021/jp207563h)
(5) “Mechanism of the Palladium-Catalyzed Addition of Arylboronic Acids to Enones: A Computational Study” Lan, Y.; Houk, K. N.* J. Org. Chem. 2011, 76, 4905-4909. (DOI: 10.1021/jo2002903)
(4) “Extraordinary Difference in Reactivity of Ozone (OOO) and Sulfur Dioxide (OSO): A Theoretical Study” Lan, Y.; Wheeler, S. E.; Houk, K. N.* J. Chem. Theory Comput. 2011, 7, 2104-2111. (DOI: 10.1021/jo902163v)
(3) “A Theoretical Investigation on the Mechanism of a Palladium-Mediated Formal 6π Electrocyclic Synthesis of 9,10-Dihydrophenanthrenes” Lan, Y.; Wang, C.; Sowa, J. R., Jr.; Wu, Y. D.* J. Org. Chem. 2010, 75, 951-954. (DOI: 10.1021/jo902163v)
(2) “Mechanism and Stereoselectivity of the Stepwise 1,3-Dipolar Cycloadditions between a Thiocarbonyl Ylide and Electron-Deficient Dipolarophiles: A Computational Investigation” Lan, Y.; Houk, K. N.* J. Am. Chem. Soc. 2010, 132, 17921-17927. (DOI: 10.1021/ja108432b)
(1) “On the Mechanism of the Palladium Catalyzed Intramolecular Pauson-Khand-Type Reaction” Lan, Y.; Deng, L.; Liu, J.; Wang, C.; Wiest, O.; Yang, Z.*; Wu, Y. D.* J. Org. Chem. 2009, 74, 5049-5058. (DOI: 10.1021/jo900919v)
（三）共同作者论文
(22) “Oxidation-induced C–H amination leads to a new avenue to build C–N bonds” Yi, H.; Tang, Z.; Bian, C.; Chen, H.; Qi, X.; Yue, X.;Lan, Y.; Lee, J.-F.; Lei, A.* Chem. Commun. 2017, 53, 8984-8987. (DOI: 10.1039/c7cc04955b)
(21) “Coordination strategy-induced selective C–H amination of 8-aminoquinolines” Yi, H.; Chen, H.; Bian, C.; Tang, Z.; Singh, A. K.; Qi, X.; Yue, X.; Lan, Y.; Lee, J.-F.; Lei, A.* Chem. Commun. 2017, 53, 6736-6739. (DOI: 10.1039/c7cc02601c)
(20) “Unravelling the hidden link of lithium halides and application in the synthesis of organocuprates” Yi, H.; Yang, D.; Xin, J.; Qi, X.;Lan, Y.; Deng, Y.*; Pao, C.-W.; Lee, J.-F.; Lei, A.* Nat. Commun. 2017, 8, 14794. (DOI: 10.1038/ncomms14794)
(19) “Highly enantioselective nitro-Mannich reaction of ketimines under phase-transfer catalysis” Wang, B.; Xu, T.; Zhu, L.; Lan, Y.; Wang, J.; Lu, N.; Wei, Z.; Lin, Y.*; Duan, H. Org. Chem. Front. 2017, 4, 1266-1271. (DOI: 10.1039/C7QO00124J)
(18) “Aromatic C–H bond cleavage by using a Cu(I) ate-complex” Zhang, G.; Yi, H.; Xin, J.; Deng, Y.; Bai, R.; Huang, Z.; Miller, J. T.; Kropf, A. J.; Bunel, E. E.; Qi, X.; Lan, Y.; Lei, A.* Org. Chem. Front. 2016, 3, 975-978. (DOI: 10.1039/c6qo00201c)
(17) “Catalytic N-radical cascade reaction of hydrazones by oxidative deprotonation electron transfer and TEMPO mediation” Hu, X.-Q.; Qi, X.; Chen, J.-R.*; Zhao, Q.-Q.; Wei, Q.; Lan, Y.; Xiao, W.-J. Nat. Commun. 2016, 7, 11188. (DOI: 10.1038/ncomms11188)
(16) “Homolytic cleavage of the O–Cu(II) bond: XAFS and EPR spectroscopy evidence for one electron reduction of Cu(II) to Cu(I)” Yi, H.; Zhang, G.; Xin, J.; Deng, Y.; Miller, J. T.; Kropf, A. J.; Bunel, E. E.; Qi, X.; Lan, Y.; Lee, J.-F.; Lei, A.* Chem. Commun. 2016, 52, 6914-6917. (DOI: 10.1039/c6cc01413e)
(15) “Tuning the Reactivity of Radical through a Triplet Diradical Cu(II) Intermediate in Radical Oxidative Cross-Coupling” Zhou, L.; Yi, H.; Zhu, L.; Qi, X.; Jiang, H.; Liu, C.; Feng, Y.; Lan, Y.; Lei, A.* Sci. Rep. 2015, 5, 15934. (DOI: 10.1038/srep15934)
(14) “Carboxylate-Assisted C(sp3)−H Activation in Olefin Metathesis-Relevant Ruthenium Complexes” Cannon, J. S.; Zou, L.; Liu, P.; Lan, Y.; O'Leary, D. J.; Houk, K. N.*; Grubbs, R. H.* J. Am. Chem. Soc. 2014, 136, 6733-6743. (DOI: 10.1021/ja5021958)
(13) “Mechanism and Enantioselectivity in Palladium-Catalyzed Conjugate Addition of Arylboronic Acids to β Substituted Cyclic Enones: Insights from Computation and Experiment” Holder, J. C.; Zou, L.; Marziale, A. N.; Liu, P.; Lan, Y.; Gatti, M.; Kikushima, K.; Houk, K. N.*; Stoltz, B. M.* J. Am. Chem. Soc. 2013, 135, 14996-15007. (DOI: 10.1021/ja401713g)
(12) “Understanding Reactivity and Stereoselectivity in Palladium-Catalyzed Diastereoselective sp3 C−H Bond Activation: Intermediate Characterization and Computational Studies” Giri, R.; Lan, Y.; Liu, P.; Houk, K. N.*; Yu, J. Q.* J. Am. Chem. Soc. 2012, 134, 14118-14126. (DOI: 10.1021/ja304643e)
(11) “Decomposition Pathways of Z-Selective Ruthenium Metathesis Catalysts” Herbert, M. B.; Lan, Y.; Keitz, B. K.; Liu, P.; Endo, K.; Day, M. W.; Houk, K. N.*; Grubbs, R. H.* J. Am. Chem. Soc. 2012, 134, 7861-7866. (DOI: 10.1021/ja301108m)
(10) “A novel self-promoted Morita-Baylis-Hillman-like dimerization” Li, Q.; Wongkhan, K.; Luo, X.; Batsanov, A. S.; Howard, J. A. K.;Lan, Y.; Wu, Y.*; Marder, T. B.*; Lei, A.* Chin. Sci. Bull. 2010, 55, 2794-2798. (DOI: 10.1007/s11434-010-3270-9)
(9) “Base-Induced Mechanistic Variation in Palladium-Catalyzed Carbonylation of Aryl Iodides” Hu, Y.; Liu, J.; Lu, Z.; Luo, X.; Zhang, H.;Lan, Y.; Lei, A.* J. Am. Chem. Soc. 2010, 132, 3153-3158. (DOI: 10.1021/ja909962f)
(8) “Revealing a Second Transmetalation Step in the Negishi Coupling and Its Competition with Reductive Elimination: Improvement in the Interpretation of the Mechanism of Biaryl Syntheses” Liu, Q.; Lan, Y.; Liu, J.; Li, G.; Wu, Y. D.*; Lei, A.* J. Am. Chem. Soc. 2009, 131, 10201-10210. (DOI: 10.1021/ja903277d)
(7) “Revelation of the Difference between Arylzinc Reagents Prepared from Aryl Grignard and Aryllithium Reagents Respectively: Kinetic and Structural Features” Jin, L.; Liu, C.; Liu, J.; Hu, F.; Lan, Y.; Batsanov, A. S.; Howard, J. A.; Marder, T. B.*; Lei, A.* J. Am. Chem. Soc. 2009, 131, 16656-16657. (DOI: 10.1021/ja908198d)
(6) “Stereoselective Construction of an Unprecedented 7-8 Fused Ring System in Micrandilactone A by [3,3]-Sigmatropic Rearrangement” Zhang, Y.-D.; Ren, W.-W.; Lan, Y.; Xiao, Q.; Wang, K.; Xu, J.; Chen, J.-H.*; Yang, Z.* Org. Lett. 2008, 10, 665-668. (DOI: 10.1021/ol703126q)
(5) “Effect of Lithium Chloride on Tuning the Reactivity of Pauson–Khand Reactions Catalyzed by Palladium–Tetramethylthiourea” Yang, Z.*; Lei, A.*; Chen, J.-H.*; Deng, L.-J.; Liu, J.; Huang, J.-Q.; Hu, Y.; Chen, M.; Lan, Y. Synthesis 2007, 2007, 2565-2570. (DOI: 10.1055/s-2007-983796)
(4) “Synthesis of Thiourea-Oxazolines, a New Class of Chiral S,N-Heterobidentate Ligands: Application in Pd-Catalyzed Asymmetric Bis(methoxycarbonylation) of Terminal Olefins” Liang, B.; Liu, J.; Gao, Y.-X.; Wongkhan, K.; Shu, D.-X.; Lan, Y.; Li, A.; Batsanov, A. S.; Howard, J. A. H.; Marder, T. B.*; Chen, J.-H.*; Yang, Z.* Organometallics 2007, 26, 4756-4762. (DOI: 10.1021/om700311x)
(3) “Convenient and Efficient Synthesis of 1,1-Bis-(4-alkylthiophenyl)-1-alkenes via Tandem Friedel–Crafts Acylation and Alkylation of Sulfides and Acyl Chlorides” Xu, J.*; Xia, J.; Lan, Y. Synth. Commun. 2005, 35, 2347-2353. (DOI: 10.1080/00397910500187373)
(2) “Mildly and Highly Selective Reductive Deoxygenation of para-Di- and Monoalkylaminophenyl Ketones by Borane” Wei, T.; Lan, Y.; Xu, J.* Heteroat. Chem. 2005, 16, 2-5. (DOI: 10.1002/hc.20062)
(1) “Chiral Oxazaborolidine-catalyzed Asymmetric Borane Reduction of Alkyl 4-Dialkylaminophenyl Ketones” Xu, J.-X.*; Lan, Y.; Wei, T.-Z.; Zhang, Q.-H. Chin. J. Chem. 2005, 23, 1457-1461. (DOI: 10.1002/cjoc.200591457)
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发表于 2018-5-28 17:15:07
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