厦门大学化学化工学院化学生物学系高锦豪

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高锦豪,厦门大学教授。课题组主要从事纳米生物，生物无机化学与活体成像分析的交叉研究工作，现任厦门大学化学化工学院教授，固体表面物理化学国家重点实验室固定研究人员。2010年入选教育部 “新世纪优秀人才支持计划”，2012年国家基金委优秀青年科学基金资助，现主持国家“973”课题、国家基金等多个项目。

课题组现在的研究领域：功能分子和纳米颗粒的设计合成及其生物医学分析应用研究：生物探针，体外诊断，分子影像及成像分析，药物输送，肿瘤诊断治疗。

高锦豪

高锦豪/Jinhao Gao
教授、博士生导师
电话：86-592-2180278
传真：86-592-2189959
办公室：卢嘉锡楼528室
电子邮箱：jhgao@xmu.edu.cn
课题组网站：http://chem.xmu.edu.cn/group/jhgao/

更新个人信息

个人简历：

学士（南京大学 2004）
博士（香港科技大学 2008）
博士后（斯坦福大学 2010）
教授（厦门大学 2010.6-）
香港青年科学家奖 (2007)，教育部“新世纪优秀人才支持计划”（2010），福建省“闽江学者”特聘教授（2011），国家基金委优秀青年科学基金项目资助（2012），福建省杰出青年科学基金资助（2012），福建省青年拔尖创新人才（2014），中国化学会青年化学奖（2014）

研究兴趣：
功能分子和纳米颗粒的设计合成及其生物医学分析应用研究：生物探针，体外诊断，分子影像及成像分析，药物输送，肿瘤诊断治疗。

近期主要代表论著：

(1) Zhou, Z. J.; Wu, C. Q.; Liu, H. Y.;Zhu, X. L.; Zhao, Z. H.; Wang, L. R.;  Xu, Y.; Ai, H.; Gao, J. H.*Surface and Interfacial Engineering of Iron Oxide Nanoplates for HighlyEfficient Magnetic Resonance Angiography. ACS Nano 2015, 9,3012-3022.
(2) Zhao, Z. H.; Wang, X. M.; Zhang, Z. J.; Zhang, H.; Liu, H. Y.; Zhu, X. L.;Li, H.; Chi, X. Q.; Yin, Z. Y.; Gao, J. H.* Real-Time Monitoring ofArsenic Trioxide Release and Delivery by Activatable T1 Imaging. ACSNano 2015, 9, 2749-2759.
(3) Zhu, X. L.; Hu, J; Zhao, Z. H.; Sun, M. J.; Chi, X. Q.; Wang, X. M.; Gao,J. H.* Kinetic and Sensitive Analysis of Tyrosinase Activity Using ElectronTransfer Complexes: In Vitro and Intracellular Study. Small 2015,11, 862-870.
(4) Zhou, Z. J.; Zhu, X.; Wu, D.; Chen, Q.; Huang, D.; Sun, C.; Xin, J.; Ni,K.; Gao, J. H.*  Anisotropic Shaped Iron Oxide Nanostructures:Controlled Synthesis and Proton Relaxation Shortening Effects. Chem.Mater. 2015, 27, 3505-3515.
(5) Wang, L. R.; Zhu, X. L.; Tang, X. Y.; Wu, C. Q.; Zhou, Z. J.; Sun, C. J.;Deng, S. L.; Ai, H.;  Gao, J. H.* A Multiple GadoliniumComplexes Decorated Fullerene as a Highly Sensitive T1 Contrast Agent. Chem.Commun. 2015, 51, 4390-4393.
(6) Zhu, X.; Chi, X.; Chen, J.; Wang, L.; Wang, X.; Chen, Z.; Gao, J.H.* Real-Time Monitoring in Vivo Behaviors of TheranosticNanoparticles by Contrast-Enhanced T1 Imaging. Anal. Chem. 2015,87, 8941-8948.
(7) Yang, L. J.; Zhou, Z.; Liu, H.; Wu, C.; Zhang, H.; Huang, G.; Ai, H.; Gao,J. H.* Europium-engineered iron oxide nanocubes with high T1 and T2contrast abilities for MRI in living subjects. Nanoscale 2015,7, 6843-6850.
(8) Huang, G. M.; Zhu, X. L.; Li, H; Wang, L. R.; Chi, X. Q.; Chen, J. H.;Wang, X. M.; Chen, Z.; Gao, J. H.* Facile integration of multiplemagnetite nanoparticles for theranostics combining efficient MRI and thermaltherapy. Nanoscale 2015, 7, 2667-2675.
(9) Zhou, Z. J.; Zhao, Z. H.; Zhang, H.; Wang, Z. Y.;  Chen, X. Y.; Wang,R. F.; Chen, Z.; Gao, J. H.* Interplay between Longitudinal andTransverse Contrasts in Fe3O4 Nanoplates with (111) Exposed Surfaces. ACSNano 2014, 8, 7976-7985.
(10) Huang, G. M.; Li, H; Chen, J. H.; Zhao, Z. H.; Yang, L. J.; Chi, X. Q.;Chen, Z.; Wang, X. M.; Gao, J. H.* Tunable T1 and T2 ContrastAbilities of Manganese-engineered Iron Oxide Nanoparticles through SizeControl. Nanoscale 2014, 6, 10404-10412.
(11) Huang, G. M.; Hu, J; Zhang, H.; Zhou, Z. J.; Chi, X. Q.; Gao, J.H.* Highly Magnetic Iron Carbide Nanoparticles as Effective T2 ContrastAgents. Nanoscale 2014, 6, 726-730.
(12) Zhao, Z. H.; Zhou, Z. J.; Bao, J. F.; Wang, Z.; Hu, J.; Chi, X.; Ni, K.;Wang, R. F.; Chen, X. Y.; Chen, Z.; Gao, J. H.* Octapod Iron OxideNanoparticles as High-performance T2 Contrast Agents for Magnetic ResonanceImaging. Nature Commun. 2013, 4, 2266.
(13) Zhou, Z. J.; Wang, L. R.; Chi, X. Q.; Bao, J. F.; Yang, L. J.; Zhan, W.X.; Chen, Z.; Wang, X. M.; Chen, X. Y.; Gao, J. H.* EngineeredIron-oxide-based Nanoparticles as Enhanced T1 Contrast Agents for EfficientTumor Imaging. ACS Nano 2013, 7, 3287-3296.
(14) Zhou, Z. J.; Huang, D. T.; Bao, J. F.; Chen, Q. L.; Liu, G.; Chen, Z.;Chen, X. Y.; Gao, J. H.* A Synergistically Enhanced T1-T2Dual-Modal Contrast Agent. Adv. Mater. 2012, 24, 6223-6228.
(15) Zhao, Z. H.; Huang, D. T.; Yin, Z. Y.; Chi, X. Q.; Wang, X. M.; Gao,J. H.* Magnetite Nanoparticles as Smart Carriers to Manipulate theCytotoxicity of Anticancer Drugs: Magnetic Control and pH-ResponsiveRelease. J. Mater. Chem. 2012, 22, 15717-15725.
(16) Chi, X. Q.; Huang, D.T.; Zhao, Z. H.; Zhou, Z. J.; Yin, Z. Y.; Gao,J. H.* Nanoprobes for In Vitro Diagnostics of Cancer and InfectiousDiseases. Biomaterials 2012, 33, 189-206.
(17) Gao, J. H.; Chen, K.; Luong, R.; Bouley, D. M.; Mao, H.; Qiao,T.; Gambhir, S. S.; Cheng, Z.* A Novel Clinically Translatable FluorescentNanoparticle for Targeted Molecular Imaging of Tumors in Living Subjects. NanoLett. 2012, 12, 281-286.
(18) Gao, J. H.; Gu, H. W.; Xu, B.* Multifunctional MagneticNanoparticles: Design, Synthesis, and Biomedical Applications. Acc.Chem. Res. 2009, 42, 1097-1107.
(19) Gao, J. H.; Liang, G. L.; Cheung, S. C.; Pan, Y.; Kuang, Y.;Zhao, F.; Zhang, B.; Zhang, X. X.; Wu, E. X.; Xu, B.* MultifunctionalYolk-shell Nanoparticles: A Potential MRI Contrast and Anticancer Agent. J.Am. Chem. Soc. 2008, 130, 11828-11833.
(20) Gao, J. H.; Zhang, W.; Huang, P. B.; Zhang, B.; Zhang, X. X.;Xu, B.* Intracellular Control of Fluorescent Magnetic Nanoparticles. J.Am. Chem. Soc. 2008, 130, 3710-3711.
(21) Gao, J. H.; Zhang, B.; Gao, Y.; Pan, Y.; Zhang, X. X.; Xu, B.*Fluorescent Magnetic Nanocrystals by Sequential Addition of Reagents in aOne-Pot Reaction: A Simple Preparation for MultifunctionalNanostructures. J. Am. Chem. Soc. 2007, 129,11928-11935.
(22) Gao, J. H.; Liang, G. L.; Zhang, B.; Kuang, Y.; Zhang, X. X.;Xu, B.* FePt@CoS2 Yolk-shellNanocrystals as a Potent Agent to Kill HeLa Cells. J. Am. Chem. Soc. 2007,129, 1428-1433.
(23) Gao, J. H.; Li, L. H.; Ho, P. L.; Mak, G. C.; Gu, H. W.; Xu,B.* Combining Fluorescent Probes and Biofunctional Magnetic Nanoparticles forRapid Detection of Bacteria in Human Blood. Adv. Mater. 2006,18, 3145-3148.
(24) Gao, J. H.; Zhang, B.; Zhang, X. X.; Xu, B.* Magnetic DipolarInteraction Induced Self-Assembly Affords Wires of Cobalt Selenide HollowNanoscrystals. Angew. Chem. Int. Ed. 2006, 45, 1220-1223.