中国科学院长春应用化学研究所中国科学院合成橡胶重点实验室李云琦

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李云琦，性别：男，1980年出生，籍贯：四川，毕业于中国科学院长春应用化学研究所，获得博士学位，教授/研究员/博士生导师，从事高性能材料基础的多学科交叉研究工作。
主要学习工作经历：
1997.9～2001.7 南京大学化学系，理学学士
2001.9～2007.3 中科院长春应化所高分子化学与物理重点实验室，理学博士
2005.5～2006.5 Rutgers大学食品系，交换学生
2007.5～2009.1 Kansas大学分子生物中心，博士后
2009.2～2010.5 Kansas大学应用生物信息实验室，博士后
2010.6～2012.11 Rutgers大学食品系，博士后
2013.1～至今 中科院长春应化所，研究员，博士生导师
     在化学和高分子物理化学学习研究经历的基础上，对分子生物学、生物信息学、蛋白质和食品科学以及高分子复合物等多个领域具有深入研究，阐述了一系列复杂体系的基本物理问题，开发了软件/服务器促进相关领域的深入研究。在以相互作用、分子构象、微结构、聚集和相行为、宏观性质的多个尺度相互联系为主线，拓展了基础物理理论模型在大分子复杂体系的应用，整合了一套对复杂体系行之有效的理论、模拟与实验相结合的多学科交叉研究方法。迄今，已发布了开源软件/服务器6个，在J. Phys. Chem. B, J. Chem. Phys.，Bioinformatics, BMC Bioinformatics, PLoS One，Proteins，Carbohydr. Polym.和Food Hydrocolloids等SCI核心期刊共发表论文30余篇，它引200余次，获得一项美国授权专利。
主要承担项目：
中科院长春应用化学研究所启动基金，中科院百人计划，自然科学基金
论文发表：
(1-31)
1.            Xia S, Li Y, Xia Q, Zhang X, & Huang Q  Glycosylation of bovine serum albumin via Maillard reaction prevents epigallocatechin-3-gallate-induced protein aggregation. Food Hydrocolloids 2015, 43(0):228-235.
2.            Li Y, Zhao Q, & Huang Q  Understanding complex coacervation in serum albumin and pectin mixtures using a combination of the Boltzmann equation and Monte Carlo simulation. Carbohydr. Polym. 2014, 101(0):544-553.
3.            Li Y, An L, & Huang Q  Replica Exchange Monte Carlo Simulation of Human Serum Albumin–Catechin Complexes. J. Phys. Chem. B 2014, 118(35):10362-10372.
4.            Duan XZ, Zhang R, Li YQ, Yang YB, Shi TF, An LJ, & Huang QR  Effect of polyelectrolyte adsorption on lateral distribution and dynamics of anionic lipids: a Monte Carlo study of a coarse-grain model. Eur Biophys J Biophy 2014, 43(8-9):377-391.
5.            Duan XZ, Li YQ, Zhang R, Shi TF, An LJ, & Huang QR  Compositional redistribution and dynamic heterogeneity in mixed lipid membrane induced by polyelectrolyte adsorption: Effects of chain rigidity. Eur Phys J E 2014, 37(8):71.
6.            Li Y & Huang Q  Influence of Protein Self-Association on Complex Coacervation with Polysaccharide: A Monte Carlo Study. J. Phys. Chem. B 2013, 117(9):2615-2624.
7.            Li J, Li Y, Lee T-C, & Huang Q  Structure and Physical Properties of Zein/Pluronic F127 Composite Films. J. Agric. Food Chem. 2013, 61(6):1309-1318.
8.            Duan X, Zhang R, Li Y, Shi T, An L, & Huang Q  Monte Carlo Study of Polyelectrolyte Adsorption on Mixed Lipid Membrane. J. Phys. Chem. B 2013, 117(4):989-1002.
9.            Duan X, Li Y, Zhang R, Shi T, An L, & Huang Q  Regulation of anionic lipids in binary membrane upon the adsorption of polyelectrolyte: A Monte Carlo simulation. AIP Adv. 2013, 3:062128.
10.         Duan X, Li Y, Shi T, Huang Q, & An L  Mutation induced structural variation in membrane proteins: Small but hard to catch. Chemical Research in Chinese Universities 2013, 29(5):1016-1021.
11.         Li Y, Zhang J, Tai D, Russell Middaugh C, Zhang Y, & Fang J  Prots: A fragment based protein thermo-stability potential. Proteins: Structure, Function, and Bioinformatics 2012, 80(1):81-92.
12.         Li Y, Shi T, An L, & Huang Q  Monte Carlo Simulation on Complex Formation of Proteins and Polysaccharides. J. Phys. Chem. B 2012, 116(10):3045-3053.
13.         Li Y, Li J, Xia Q, Zhang B, Wang Q, & Huang Q  Understanding the Dissolution of α-Zein in Aqueous Ethanol and Acetic Acid Solutions. J. Phys. Chem. B 2012, 116(39):12057-12064.
14.         Li Y & Fang J  PROTS-RF: A Robust Model for Predicting Mutation-Induced Protein Stability Changes. PLoS One 2012, 7(10):e47247.
15.         Li Y, Xia Q, Shi K, & Huang Q  Scaling Behaviors of α-Zein in Acetic Acid Solutions. J. Phys. Chem. B 2011, 115(32):9695-9702.
16.         Li Y, Fang Y, & Fang J  Predicting residue-residue contacts using random forest models. Bioinformatics 2011, 27(24):3379-3384.
17.         Li Y, Middaugh CR, & Fang J  A novel scoring function for discriminating hyperthermophilic and mesophilic proteins with application to predicting relative thermostability of protein mutants. BMC Bioinformatics 2010, 11(1):62.
18.         Li Y & Fang J  Distance-dependent statistical potentials for discriminating thermophilic and mesophilic proteins. Biochem. Biophys. Res. Commun. 2010, 396(3):736-741.
19.         Li Y & Zhang Y  REMO: A new protocol to refine full atomic protein models from C-alpha traces by optimizing hydrogen-bonding networks. Proteins: Structure, Function, and Bioinformatics 2009, 76(3):665-676.
20.         Li Y, Roy A, & Zhang Y  HAAD: A Quick Algorithm for Accurate Prediction of Hydrogen Atoms in Protein Structures. PLoS One 2009, 4(8):e6701.
21.         Song J, Shi T, Li Y, Chen J, & An L  Rigidity effect on phase behavior of symmetric ABA triblock copolymers: A Monte Carlo simulation. J. Chem. Phys. 2008, 129(5):054906.
22.         Li Y, Lee J, Lal J, An L, & Huang Q  Effects of pH on the Interactions and Conformation of Bovine Serum Albumin: Comparison between Chemical Force Microscopy and Small-Angle Neutron Scattering. J. Phys. Chem. B 2008, 112(12):3797-3806.
23.         Wang X, Li Y, Wang YW, Lal J, & Huang Q  Microstructure of beta-lactoglobulin/pectin coacervates studied by small-angle neutron scattering. J. Phys. Chem. B 2007, 111(3):515-520.
24.         Song J, Li Y, Huang Q, Shi T, & An L  Monte Carlo simulation on symmetric ABA/AB copolymer blends in confined thin films. J. Chem. Phys. 2007, 127(9):094903.
25.         Li Y, Shi T, An L, Lee J, Wang X, & Huang Q  Effects of polar group saturation on physical gelation of amphiphilic polymer solutions. J. Phys. Chem. B 2007, 111(42):12081-12087.
26.         Li Y, Shi T, Sun Z, An L, & Huang Q  Investigation of sol-gel transition in pluronic F127/D2O solutions using a combination of small-angle neutron scattering and Monte Carlo simulation. J. Phys. Chem. B 2006, 110(51):26424-26429.
27.         Li Y, Huang Q, Shi T, & An L  How does solvent molecular size affect the microscopic structure in polymer solutions? J. Chem. Phys. 2006, 125(4):044902.
28.         Li Y, Huang Q, Shi T, & An L  Effects of chain flexibility on polymer conformation in dilute solution studied by lattice Monte Carlo simulation. J. Phys. Chem. B 2006, 110(46):23502-23506.
29.         Liao Y, Su Z, Ye X, Li Y, You J, Shi T, & An L  Kinetics of Surface Phase Separation for PMMA/SAN Thin Films Studied by in Situ Atomic Force Microscopy. Macromolecules 2005, 38(2):211-215.
30.         Li Y, Sun Z, Su Z, Shi T, & An L  The effect of solvent size on physical gelation in triblock copolymer solutions. J. Chem. Phys. 2005, 122(19):194909.
31.         Li Y, Sun Z, Shi T, & An L  Conformation studies on sol-gel transition in triblock copolymer solutions. J. Chem. Phys. 2004, 121(2):1133-1140.