国家纳米科学中心中科院纳米生物效应与安全性重点实验室李乐

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李乐乐，研究员，博士生导师。2010年于北京大学获博士学位，导师为严纯华院士。2010-2012年在美国伊利诺伊大学香槟分校(UIUC)进行博士后研究，合作导师为Yi Lu教授；2012-2016年麻省理工学院(MIT)和哈佛医学院(HMS)进行博士后研究，合作导师为Robert Langer院士和Daniel S. Kohane教授。2016年7月加入国家纳米科学中心。目前已在PNAS，JACS，Angew Chem Int Ed，Chem Mater和Small等国际学术期刊上发表学术论文30余篇。
姓    名:李乐乐        
性    别:男
职    务:无        
职    称:研究员
通讯地址:北京市海淀区中关村北一条11号
邮政编码:100190        
电子邮件:lilele@nanoctr.cn        

研究领域：
　　纳米生物材料 & 纳米生物技术
获奖及荣誉：        
　　 2010  北京大学优秀博士论文
　　 2009  钟陈玉兰奖一等奖
代表论著：
　　1. Le-Le Li, Yi Lu*, “Regiospecific Hetero-Assembly of DNA-Functionalized Plasmonic Upconversion Superstructures” J. Am. Chem. Soc. 2015, 137, 5272.
　　2. Lele Li, Rong Tong, Hunghao Chu, Weiping Wang, Robert Langer*, Daniel S. Kohane*, “Aptamer Photoregulation In Vivo” Proc. Natl. Acad. Sci. U.S.A. 2014, 111, 17099.  
　　3. Xiaoxia Hu, Ting Wei, Jie Wang, Zi-En Liu, Xinyang Li, Binhao Zhang, Zhihao Li, Lele Li*, Quan Yuan*, “Near-Infrared-Light Mediated Ratiometric Luminescent Sensor for Multimode Visualized Assays of Explosives” Anal. Chem. 2014, 86, 10484.  
　　4. Le-Le Li, Peiwen Wu, Kevin Hwang, Yi Lu*, “An Exceptionally Simple Strategy for DNA-Functionalized Up-Conversion Nanoparticles as Biocompatible Agents for Nanoassembly, DNA Delivery, and Imaging” J. Am. Chem. Soc. 2013, 135, 2411.
　　5. Le-Le Li, Mengying Xie, Jie Wang, Xinyang Li, Cheng Wang, Quan Yuan*, Dai-Wen Pang*, Yi Lu*, Weihong Tan, “A Vitamin-responsive Mesoporous Nanocarrier with DNA Aptamer-mediated Cell Targeting” Chem. Commun. 2013, 49, 5823.   
　　6. Le-Le Li, Ruobing Zhang, Leilei Yin, Kezhi Zheng, Weiping Qin, Paul R. Selvin, Yi Lu*, “Biomimetic Surface Engineering of Lanthanide-Doped Upconversion Nanoparticles as Versatile Bioprobes” Angew. Chem., Int. Ed. 2012, 51, 6121.
　　7. Le-Le Li, Qian Yin, Jianjun Cheng, Yi Lu*, “Polyvalent Mesoporous Silica Nanoparticle-Aptamer Bioconjugates Target Breast Cancer Cells” Adv. Healthcare Mater. 2012, 1, 567.  
　　8. Le-Le Li, Pinghua Ge, Paul R. Selvin, Yi Lu*, “Direct Detection of Adenosine in Undiluted Serum Using a Luminescent Aptamer Sensor Attached to a Terbium Complex” Anal. Chem. 2012, 84, 7852.
　　9. Le-Le Li, Xue-Feng Fu, Zhen Ren, Ya-Guang Zhao, Wei Feng, Chun-Hua Yan*, “Hierarchical Self-Assembly of Superlattice Hybrids Consisting of Periodic and Alternating Cores of Porphyrin Molecules Separated by Nanoscale Silica Walls” Langmuir 2010, 26, 15730.
　　10. Le-Le Li, Hao Sun, Yan-Chun Bai, Chen-Jie Fang, Chun-Hua Yan*, “Orientational Organization of Organic Semiconductors within Periodic Nanoscale Silica Channels: Modification of Fluorophore Photophysics through Hierarchical Self-Assembly” Chem. Eur. J. 2009, 15, 4716.
　　11. Le-Le Li, Jun Xu, Quan Yuan, Zhen-Xing Li, Wei-Guo Song, Chun-Hua Yan*, “Facile Synthesis of Macrocellular Mesoporous Foam-like Ce-Sn Mixed Oxide with Nanocrystalline Frameworks by Using Triblock Copolymer as Single-Template” Small 2009, 5, 2730.
　　12. Le-Le Li, Hao Sun, Chen-Jie Fang, Quan Yuan, Ling-Dong Sun, Chun-Hua Yan*, “Mesostructured Hybrids Containing Potential Donors and Acceptors with Molecular-scale and Meso-scale Segregation and Ordering: Toward the Development of Smart Materials through Hierarchical Self-assembly” Chem. Mater. 2009, 21, 4589.
　　13. Le-Le Li, Wen-Tao Duan, Quan Yuan, Zhen-Xing Li, Hao-Hong Duan, Chun-Hua Yan*, “Hierarchical g-Al2O3 Monoliths with Highly Ordered 2D Hexagonal Mesopores in Macroporous Walls” Chem. Commun. 2009, 6174.
　　14. Le-Le Li, Ling-dong Sun, Ya-Wen Zhang, Chun-Hua Yan*, “Functional-Template Directed Self-Assembly (FTDSA) of Mesostructured Organic–Inorganic Hybrid Materials” Sci. China Ser. B 2009, 52, 1759.
　　15. Le-Le Li, Chen-Jie Fang, Hao Sun, Chun-Hua Yan*, “Hierarchical Self-assembly of pH-Responsive Nanocomposites with Molecular-scale and Mesoscale Periodicities” Chem. Mater. 2008, 20, 5977.
　　16. Le-Le Li, Wei-Ming Zhang, Quan Yuan, Zhen-Xing Li, Chen-Jie Fang, Ling-Dong Sun, Li-Jun Wan, Chun-Hua Yan*, “Room Temperature Ionic Liquids Assisted Green Synthesis of Nanocrystalline Porous SnO2 and Their Gas Sensor Behaviors” Cryst. Growth Des. 2008, 8, 4165.
　　17. Le-Le Li, Chen-Jie Fang, Quan Yuan, Chun-Hua Yan*, “Stabilization of Facial Isomer of Tris(8-hydroxyquinolinate) Aluminum though Confinement in Silica-Surfactant Mesostructures” Appl. Phys. Lett. 2007, 90, 231908.
　　18. Le-Le Li, Hao Sun, Chen-Jie Fang, Jun Xu, Jing-Yi Jin, Chun-Hua Yan*, “Optical Sensors Based on Functionalized Mesoporous Silica SBA-15 for the Detection of Multianalytes (H+, Cu2+) in Water” J. Mater. Chem. 2007, 17, 4492.