陕西师范大学化学化工学院分析化学高强

zhongyuzhong

高　强
职  称：教授
毕业学校：中国科学院长春应用化学研究所（博士）　日本东北大学 （博士后）
电  话：
电子邮箱：gaoqiang@snnu.edu.cn
研究方向：生物传感器及DNA损伤检测
个人简介
　　2003年在中国科学院长春应用化学研究所获得分析化学专业博士学位，期间主要从事电化学生物传感器的研究。2004年获得日本科学技术振兴机构 (JST，Japan Science and Technology Agency) 的资助，在日本东北大学 (Tohoku University) 从事了两年博士后研究。期间开展了DNA损伤检测和单核苷酸多态性方面研究，利用荧光和表面等离子体共振 (SPR) 技术研究含氮杂环小分子和ds-DNA中未配对碱基的相互作用及识别。
　　2006年至今在陕西师范大学化学化工学院工作，主要从事电化学和表面等离子体共振生物传感器的研究。主持国家自然科学基金面上项目（信号放大外周血循环肿瘤细胞电化学检测新方法研究，编号21175089，60万），国家自然科学青年基金项目 (表面等离子体共振单核苷酸多态性分型新方法研究，编号20805029，22万)、教育部留学回国人员基金 (2万) 和中国科学院长春应用化学研究所电分析化学国家重点实验室开放基金项目 (编号2007003, 3万)。参与国家863项目 (百米级强钉扎涂层导体关键技术研究，编号：2008AA03Z201)子项目。在Chem. Commun., Biosens. Bioelectron., Electrochem. Commun., Anal. Chem.等SCI源期刊上发表论文10多篇，获中国发明专利1项。
代表性成果
1.Qiang Gao*, Wenyan Zhang, Yanyan Guo, Honglan Qi, Chengxiao Zhang, Highly sensitive impedimetric sensing of DNA hybridization based on the target DNA-induced displacement of gold nanoparticles attached to ssDNA probe, Electrochemistry Communications, 2011, 13(4), 335-337.
2.Wei Wang, Xiaqing Yuan, Wenyan Zhang, Qiang Gao*, Honglan Qi, Chengxiao Zhang, Cascade signal amplification for ultra-sensitive impedimetric detection of DNA hybridization using a hairpin DNA as probe, Electrochimica Acta, 2012, 78, 377-383.
3.Yunxiang Wang, Cuiping Wang, Hongyan Bo, Qiang Gao*, Honglan Qi, Chengxiao Zhang, Specific recognition of a single guanine bulge in dsDNA using a surface plasmon resonance sensor with immobilized 2-(2-aminoacetyl)amino-5,6,7-trimethyl-1,8-naphthyridine, Sensors and Actuators B, 2013, 177(1), 800-806.
4.Jing Liu, Xiaqing Yuan, Qiang Gao*, Honglan Qi, Chengxiao Zhang, Ultrasensitive DNA detection based on coulometric measurement of enzymatic silver deposition on gold nanoparticle-modified screen-printed carbon electrode, Sensors and Actuators B, 2012, 162(1), 384-390.
5.Qiang Gao*, Yanyan Guo, Wenyan Zhang, Honglan Qi, Chengxiao Zhang, An amperometric glucose biosensor based on layer-by-layer GOx-SWCNT conjugate/redox polymer multilayer on a screen-printed carbon electrode, Sensors and Actuators B, 2011, 153(1), 219-225.
6.Liangliang Hu, Yunxiang Wang, Wei Wang, Qiang Gao*, Honglan Qi, Chengxiao Zhang, Recognition Of A C–C Mismatch In A DNA Duplex Using A Fluorescent Small Molecule With Application For “Off–On” Discrimination Of C/G Mutation, Applied Spectroscopy, 2012, 66(2), 170–174.
7.Qiang Gao*, Yanyan Guo, Jing Liu, Xiaqing Yuan, Honglan Qi, Chengxiao Zhang, A biosensor prepared by co-entrapment of a glucose oxidase and a carbon nanotube within an electrochemically deposited redox polymer multilayer, Bioelectrochemistry, 2011, 81(2), 109–113.
8.Qiang Gao*, Kai Lin, Hongge Zhang, Honglan Qi, Chengxiao Zhang, Label-free fluorescent molecular beacon based on a small fluorescent molecule non-covalently bound to the intentional gap site in the stem moiety, Talanta, 2010, 83, 535-540.
9.Qiang Gao*, Meng Sun, Ping Peng, Honglan Qi, Chengxiao Zhang, Electro-oxidative polymerization of phenothiazine dyes into a multilayer-containing carbon nanotube on a glassy carbon electrode for the sensitive and low-potential detection of NADH, Microchimica Acta, 2010, 168, 299–307.
10.胡亮亮, 薄红艳, 高强*, 漆红兰, 张成孝，荧光小分子2-氨基-5,6,7-三甲基-1,8-萘啶识别dsDNA 中胞嘧啶凸出，中国科学: 化学, 2011, 41(11), 1732-1739.
11.Sara Miura, Seiichi Nishizawa, Akinori Suzuki, Yukiko Fujimoto, Katsuya Ono, Qiang Gao, Norio Teramae, DNA-binding small-ligand-immobilized surface plasmon resonance biosensor for detecting thymine-related single-nucleotide polymorphisms, Chemistry - A European Journal, 2011, 17, 14104-14110.
12.Qiang Gao, Xiurong Yang*, Layer-by-layer electrodeposition of redox polymers and enzymes on screen-printed carbon electrodes for the preparation of reagentless biosensors, Chemistry Communication, 2004, 30-31.
13.Qiang Gao, Xiaoqiang Cui, Fan Yang, Ying Ma, Xiurong Yang*, Preparation of poly(thionine) modified screen-printed carbon electrode and its application to determine NADH in flow Injection analysis system, Biosensors and Bioelectronics, 2003, 19, 277-282.