刘晓庆:女,博士 ,武汉大学化学与分子科学学院教授、博导,2003年在山东师范大学化学化工与材料科学学院取得学士学位,2009年初从中国科学院长春应用化学研究所、电分析化学国家重点实验室获得博士学位, 获中科院刘永龄奖学金特别奖。2009至2015年先后在丹麦奥胡斯大学化学系、交叉学科纳米中心以及以色列耶路撒冷希伯来大学化学研究所、纳米科学与技术中心做博士后研究工作。2015年加入武汉大学化学与分子科学学院,任教授、博导,入选国家青年##计划(2015)。
研究领域与兴趣: 传感界面、生物分析、功能化纳米/生物材料、纳米生物技术与纳米药物。包括核酸结构的组装、调控及应用;纳米传感体系的构筑与性能研究;功能化生物材料的构建及应用等。相关成果发表在J. Am. Chem. Soc., Angew. Chem. Int. Ed. (VIP论文), ACSNano, Nano Lett., Adv. Mater., Anal. Chem., Acc. Chem. Res.等国际知名期刊,其中有8篇入选ESI高引用文章,授权专利5项。 欢迎具有化学、生物或材料背景的本科生、研究生和博士后加入我们研究小组。 部分论文与专利: 1.Fuan Wang†, Xiaoqing Liu†, ItamarWillner*, DNA Switches: From Principles to Applications. Angew. Chem. Int. Ed.2015, 54, 1098-1129. (†Equal Contribution) 2.Xiaoqing Liu, Chun-Hua Lu, ItamarWillner*, Switchable Reconfiguration of Nucleic Acid Nanostructures byStimuli-Responsive DNA Machines. Acc. Chem. Res. 2014, 47, 1673–1680. 3.Lianzhe Hu†, Xiaoqing Liu†, AlessandroCecconello, Itamar Willner*, Dual Switchable CRET-Induced Luminescence ofCdSe/ZnS Quantum Dots (QDs) by the Hemin/G-Quadruplex-Bridged Aggregation andDeaggregation of Two-Sized QDs. Nano Lett. 2014, 14, 6030-6035. (†EqualContribution) 4.Fuan Wang, Chun-Hua Lu, Xiaoqing Liu,Lina Freage, Itamar Willner*, Amplified and Multiplexed Detection of DNA Usingthe Dendritic Rolling Circle Amplified Synthesis of DNAzyme Reporter Units.Anal. Chem. 2014, 86, 1614–1621. 5.Chun-Hua Lu, Xiu-Juan Qi, Xiaoqing Liu,Simcha Shimron, Huang-Hao Yang, Itamar Willner*, Autonomous Control ofInterfacial Electron Transfer and the Activation of DNA Machines by anOscillatory pH System. Nano Lett. 2013, 13, 4920–4924. 6.Xiaoqing Liu, Fuan Wang, Ruth Aizen, OmerYehezkeli, Itamar Willner*, Graphene Oxide/Nucleic Acid-Stabilized SilverNanoclusters: Functional Hybrid Materials for Optical Aptamer Sensing andMultiplexed Analysis of Pathogenic DNAs. J. Am. Chem. Soc. 2013, 135,11832–11839. 7.Fuan Wang, Xiaoqing Liu, Chun-Hua Lu,Itamar Willner*, Cysteine-Mediated Aggregation of Au Nanoparticles: TheDevelopment of a H2O2 Sensor and Oxidase-Based Biosensors. ACS Nano, 2013, 7,7278–7286. 8.Gilad Pelossof, Ran Tel-Vered, XiaoqingLiu, Itamar Willner*, Switchable Mechanical DNA “Arms” Operating on NucleicAcid Scaffolds Associated with Electrodes or Semiconductor Quantum Dots.Nanoscale, 2013, 5, 8977–8981. 9.Xiaoqing Liu, Fuan Wang, AngelicaNiazov-Elkan, Weiwei Guo, Itamar Willner*, Probing Biocatalytic Transformationswith Luminescent DNA/Ag Nanoclusters. Nano Lett. 2013, 13, 309–314. 10.Xiaoqing Liu, Angelica Niazov-Elkan,Fuan Wang, Itamar Willner*, Switching Photonic and Electrochemical Functions ofa DNAzyme by DNA Machines. Nano Lett. 2013, 13, 219–225. 11.Fuan Wang, Xiaoqing Liu, ItamarWillner*, Integration of Photoswitchable Proteins, Photosynthetic ReactionCenters and Semiconductor/Biomolecule Hybrids with Electrode Supports for OptobioelectronicApplications. Adv. Mater. 2013, 25, 349–377. 12.Xiaoqing Liu, Ruth Aizen, Ronit Freeman,Omer Yehezkeli, Itamar Willner*, Multiplexed Aptasensors and Amplified DNASensors Using Functionalized Graphene Oxide: Application for Logic Gate Operations.ACS Nano 2012, 6, 3553–3563. 13.Xiaoqing Liu, Freeman Ronit, ItamarWillner*, Amplified Fluorescence Aptamer-Based Sensors Using Exonuclease IIIfor the Regeneration of the Analyte. Chem. Eur. J. 2012, 18, 2207–2211. 14.Zhanxia Zhang, Etery Sharon, RonitFreeman, Xiaoqing Liu, Itamar Willner*, Fluorescence Detection of DNA,Adenosine-5''''''''''''''''''''''''''''''''-Triphosphate and TelomeraseActivity by Zn(II)-Protoporphyrin IX/G-Quadruplex as Label. Anal. Chem. 2012,84, 4789–4797. 15.Ronit Freeman†, Xiaoqing Liu†, ItamarWillner*, Chemiluminescent and Chemiluminescence Resonance Energy Transfer(CRET) Detection of DNA, Metal Ions, and Aptamer-Substrate Complexes UsingHemin/G-Quadruplexes and CdSe/ZnS Quantum Dots. J. Am. Chem. Soc. 2011, 133, 11597–11604.(†Equal Contribution) 16.Xiaoqing Liu, Ronit Freeman, Eyal Golub,Itamar Willner*, Chemiluminescence and Chemiluminescence Resonance EnergyTransfer (CRET) Aptamer Sensors Using Catalytic Hemin/G-Quadruplexes. ACS Nano2011, 5, 7648–7655. DOI: 17.Ronit Freeman, Xiaoqing Liu, ItamarWillner*, Amplified Multiplexed Analysis of DNA by the ExonucleaseIII-Catalyzed Regeneration of the Target DNA in the Presence of FunctionalizedSemiconductor Quantum Dots. Nano Lett. 2011, 11, 4456–4461. 18.Gilad Pelossof, Ran Tel-Vered, XiaoqingLiu, Itamar Willner*, Amplified Surface Plasmon Resonance-Based DNA Biosensors,Aptasensors, and Hg2+ Sensors Using Hemin/G-Quadruplexes and Au Nanoparticles.Chem. Eur. J. 2011, 17, 8904–8912. 19.Xiaoqing Liu, Fuan Wang, Yuling Wang,Shuyun Zhu, Guobao Xu*, Functionalized Single-Walled Carbon Nanohorns forElectrochemical Biosensing. Biosens. Bioelectron. 2010, 25, 2194-2199. 20.Xiaoqing Liu, Fuan Wang, Shuang Han,Lihong Shi, Guobao Xu*, Self-Assembly of gold Nanoparticles/ElectroactivePolyelectrolyte Multilayer Films for Tunable Electrocatalysis. Electroanalysis2010, 22, 963-969. 21.Fuan Wang, Xiaoqing Liu, Gaiping Li, DanLi, Shaojun Dong*, Selective Electrodissolution of Inorganic Ions/DNAMultilayer Film for Tunable DNA Release. J. Mater. Chem. 2009, 19, 286–291. 22.Wenxin Niu, Shanliang Zheng, Dawei Wang,Xiaoqing Liu, Haijuan Li, Shuang Han, Jiuan Chen, Zhiyong Tang*, Guobao Xu*,Selective Synthesis of Single-Crystalline Rhombic Dodecahedral, Octahedral, andCubic Gold Nanocrystals. J. Am. Chem. Soc. 2009, 131, 697–703. 23.Xiaoqing Liu, Lihong Shi, Wenxin Niu,Haijuan Li, Guobao Xu*, Amperometric Glucose Biosensor Based on Single-WalledCarbon Nanohorns. Biosens. Bioelectron. 2008, 23, 1887–1890. 24.Xiaoqing Liu, Wenxin Niu, Haijuan Li,Shuang Han, Lihong Shi, Guobao Xu*, Glucose Biosensor Based on GoldNanoparticle-Catalyzed Luminol Electrochemiluminescence on a Three-DimensionalSol-Gel Network. Electrochem. Commun. 2008, 10, 1250–1253. 25.Fuan Wang, Jianlong Wang, Xiaoqing Liu,Shaojun Dong*, Nanoparticle-amplified Surface Plasmon Resonance Study ofProtein Conformational Change at Interface. Talanta 2008, 77, 628–634. 26.Xiaoqing Liu, Lihong Shi, Wenxin Niu,Haijuan Li, Guobao Xu*, Environmentally Friendly and Highly SensitiveRuthenium(II) Tris(2,2''''''''''''''''''''''''''''''''-bipyridyl)Electrochemiluminescent System Using 2-(dibutylamino)ethanol as Co-Reactant.Angew. Chem. Int. Ed. 2007, 46, 421–424. 27.Xiaoqing Liu, Lihong Shi, Haijuan Li,Wenxin Niu, Guobao Xu*,Tris(2,2''''''''''''''''''''''''''''''''-bipyridyl)ruthenium(II)Electrochemiluminescent Detection of Coreactants Containing Aromatic Diol Groupby the Interaction Between Diol and Borate Anion. Electrochem. Commun. 2007, 9,2666–2670. 28.Jing Li, Minghua Huang, Xiaoqing Liu,Hui Wei, Yuanhong Xu, Guobao Xu, Erkang Wang*, EnhancedElectrochemiluminescence Sensor fromTris(2,2''''''''''''''''''''''''''''''''-Bipyridyl)Ruthenium(II) Incorporatedinto MCM-41 and an Ionic Liquid-Based Carbon Paste Electrode. Analyst 2007,132, 687–691. DOI: 10.1039/B701842H 29.Lihong Shi, Xiaoqing Liu, Haijuan Li,Wenxin Niu, Guobao Xu*, Application of Ceramic Carbon Materials for Solid-PhaseExtraction of Organic Compounds. Anal. Chem. 2006, 78, 1345–1348. 30.Lihong Shi, Xiaoqing Liu, Haijuan Li,Guobao Xu*, Electrochemiluminescent Detection Based on Solid-Phase Extractionat Tris(2,2''''''''''''''''''''''''''''''''-Bipyridyl)Ruthenium(II)-ModifiedCeramic Carbon Electrode. Anal. Chem. 2006, 78, 7330–7334. 专利: 1.发明人:徐国宝,刘晓庆,史立红,专利名称:环境友好的高灵敏电化学发光检测方法,专利号:200510016848.4,公开号:CN1696666,授权公告日:2010.01.27 2.发明人:徐国宝,史立红,刘晓庆,牛文新,专利名称:三联吡啶钌电化学发光测定血浆钙的方法,专利号:200510017231.4,公开号:CN1773259,授权公告日:2009.05.20 3.发明人:徐国宝, 史立红,刘晓庆,李海娟,专利名称:溶胶-凝胶法制备的碳陶瓷材料的应用,专利号:200510017012.6,公开号:CN1736581,授权公告日:2007.10.10 4.发明人:徐国宝,史立红,刘晓庆,专利名称:Nafion-碳陶瓷复合材料电化学发光传感器的制备方法,专利号:CN200510016770.6,公开号:CN1693285,授权公告日:2007.05.09 5.发明人:李景虹,王美佳,刘晓庆,专利名称:脱氧核糖核酸电化学纳米传感器的制备方法,专利号:03127158.8,公开号:CN1525163,授权公告日:2005.08.17
|