国家纳米科学中心李一叶

gaodingpiao

李一叶，国家纳米科学中心研究员。2008年毕业于中国医学科学院基础医学研究所&北京协和医学院基础学院医学分子生物学国家重点实验室，获理学博士学位；同年在国家纳米科学中心从事博士后研究；2011年加入国家纳米科学中心工作。长期从事智能纳米体系的药物递送以及纳米生物效应研究，关注胰腺癌的纳米诊疗。近年发表研究论文30余篇，其中通讯作者或第一作者论文发表于Nature Communications，Advanced Materials，Journal of the American Chemical Society，Angewandte Chemie International Edition，ACS NANO，National Science Review，Biomaterials，Nanomedicine: Nanotechnology, Biology and Medicine等国际学术期刊，部分研究成果被Nature Materials等学术期刊推荐为研究亮点。


姓    名:李一叶       
性    别:女
职    称:研究员
通讯地址:北京市海淀区中关村北一条11号
邮政编码:100190       
电子邮件:liyy@nanoctr.cn       


研究领域：       
肿瘤纳米生物学,纳米生物效应


代表论著：
2018年以来代表性论文:
1.        Xuexiang Han, Yiye Li*, Ying Xu, Xiao Zhao, Yinlong Zhang, Xiao Yang, Yongwei Wang, Ruifang Zhao, Greg J Anderson, Yuliang Zhao*, Guangjun Nie*, Reversal of Pancreatic Desmoplasia by Re-Educating Stellate Cells with a Tumour Microenvironment-Activated Nanosystem, Nature Communications, 2018, 9 (1):3390.
2.        Huan Min, Yingqiu Qi, Yinlong Zhang, Xuexiang Han, Keman Cheng, Ying Liu, Hiubiao Liu, Jianshe Hu*, Guangjun Nie*, Yiye Li*, A Graphdiyne Oxide-Based Iron Sponge with Photothermally-Enhanced Tumor-Specific Fenton Chemistry, Advanced Materials, 2020, DOI:10.1002/adma.202000038.
3.        Xuexiang Han, Keman Cheng, Ying Xu, Yazhou Wang, Huan Min, Yinlong Zhang, Xiao Zhao, Ruifang Zhao, Gregory J. Adnderson, Lei Ren, Guangjun Nie*, Yiye Li*, Modularly Designed Peptide Nanoprodrug Augments Anti-Tumor Immunity of PD-L1 Checkpoint Blockade by Targeting Indoleamine 2, 3-Dioxygenase, Journal of the American Chemical Society, 2020, 142, 2490-2496.
4.        Huan Min, Jing Wang, Yingqiu Qi, Yinlong Zhang*, Xuexiang Han, Ying Xu, Junchao Xu, Yao Li, Long Chen, Keman Cheng, Guangna Liu, Na Yang, Yiye Li*, Guangjun Nie*, Biomimetic Metal-Organic Framework Nanoparticles for Cooperative Combination of Antiangiogenesis and Photodynamic Therapy for Enhanced Efficacy, Advanced Materials, 2019, 31(15):e1808200.
5.        Xuexiang Han, Ying Xu, Yiye Li*, Xiao Zhao, Yinlong Zhang, Huan Min, Yingqiu Qi, Gregory J. Anderson, Linhao You, Yuliang Zhao*, Guangjun Nie*, An Extendable Star-like Nanoplatform for Functional and Anatomical Imaging-Guided Photothermal Oncotherapy, ACS NANO, 2019, 13(4): 4379-4391.
6.        Ying Xu, Xuexiang Han, Yiye Li*, Huan Min, Xiao Zhao, Yinlong Zhang, Yingqiu Qi, Jian Shi, Sheng Qi, Yongping Bao*, Guangjun Nie*, Sulforaphane Mediates Glutathione Depletion via Polymeric Nanoparticles to Restore Cisplatin Chemosensitivity, ACS NANO, 2019, 13(11), 13445？13455.
7.        Yiye Li, Jing Wang, Feng Zhao, Bing Bai, Guangjun Nie, André E Nel*, Yuliang Zhao*, Nanomaterial Libraries and Model Organisms for Rapid High Content Analysis of Nanosafety, National Science Review, 2018, 5(3): 365–388.
8.        Xuexiang Han, Ying Xu, Marzieh Geranpayehvagheia, Gregory J. Anderson, Yiye Li*, Guangjun Nie*, Emerging Nanomedicines for Anti-Stromal Therapy Against Desmoplastic Tumors, Biomaterials, 2020, 232, 119745.