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吕辉，博士，副教授，武汉大学化学与分子科学学院副教授，曾在新加坡南洋理工大学做博士后研究。2003年于湘潭大学获学士学位；2010年于中国科学院化学研究所获博士学位。2010年8月至2012年8月在新加坡南洋理工大学做博士后研究，2012年10月加入中国科学院化学研究所，任助理研究员。2013年11月至今在武汉大学化学与分子科学学院任教。
研究领域与兴趣 1、过渡金属催化的不对称催化反应研究 2、新型手性膦配体的合成及应用 3、催化反应在药物中间体及生物活性分子合成中的应用 研究成果 1. WenchaoGaoa, Hui Lv*, Tonghuan Zhang*, Yuhong Yang, Lung Wa Chung*,Yun-Dong Wu, Xumu Zhang*, Nickel-Catalyzed Asymmetric Hydrogenation ofß-Acylamino Nitroolefins: An Efficient Approach to Chiral Amines, ChemicalScience, 2017, 8, 6419 – 6422. 2. WenchaoGao, Hui Lv*, Xumu Zhang*, Rh/DuanPhos-Catalyzed AsymmetricHydrogenation of β-Acetylamino Vinylsulfides: An Approach to Chiralβ-Acetylamino Sulfides, Org. Lett., 2017, 19,2877–2880. 3. Yu-QingGuan, Min Gao, Xu Deng, Hui Lv*, Xumu Zhang*,Rhodium-catalyzed Asymmetric Hydrogenation of Tetrasubstitutedβ-acetoxy-α-enamido Esters and Efficient Synthesis of Droxidopa, Chem.Comm. 2017,53,53, 8136—8139. 4. XiuxiuLi, Cai You, Yusheng Yang, Fangyuan Wang, Shuailong Li, Hui Lv*,Xumu Zhang, Rhodium-catalyzed enantioselective hydrogenation of α-aminoacrylonitriles: an efficient approach to synthesizing chiral α-aminonitriles, Chem.Comm. 2017,53, 1313-1316. 5. BiaoWei, Caiyou Chen, Cai You, Hui Lv*, Xumu Zhang*,Efficient synthesis of (S,R)- Bn-Yanphos and Its Application in AsymmetricHydroformylation of vinyl heteroarenes, Org. Chem. Front. 2017,4, 288-291. 6. XiuxiuLi, Cai You, Hailong Yang, Jinteng Che, Pengyu Chen, Hui Lv*, XumuZhang*, Highly Enantioselective Rhodium-Catalyzed Hydrogenation ofTetrasubstituted Cyclic Enamides: Efficient Access to Chiral CycloalkylaminesDerivatives, Adv.Synth. Catal. 2017, 359,597–602. 7. LiyangShi, Xuefeng Tan, Jiao Long, Xiong Xiong, Song Yang, Peng Xue, HuiLv,* Xumu Zhang*, Direct Catalytic Hydrogenation of Simple Amides:A Highly Efficient Approach From amides to Amines and Alcohols, Chem.Eur. J. 2017, 23, 546 –548. 8. CaiyouChen, Shicheng Jin, Zhefan Zhang, Heng Wang, Xinrui Wang, Kai Zhang, HuiLv,* Xiu-Qin Dong,* and Xumu Zhang*, Rhodium/Yanphos-catalyzedasymmetric interrupted intramolecular hydroaminomethylation of tans-1, 2， disubstitutedalkenes: efficient synthesis of chiral pyrrolidinones and pyrrolidines, J.Am. Soc. Chem. 2016, 138, 9017-9020. 9. QingliWang, Wenchao Gao, Hui Lv,* Xumu Zhang*,Enantioselective synthesis of b-substituted Chiral Allylic Amines viaRh-Catalyzed Asymmetric Hydrogenation, Chem.Comm. 2016, 52,11850-11853. 10. Fangyuan Wang, XuefengTan, Hui Lv*, and Xumu Zhang*，New RutheniumComplexes Based on Tetradentate Bipyridine Ligands for CatalyticHydrogenationof Esters，Chem.-asian J., 2016, 11,2103-2106. 11. Guozhen Wang, Xuefeng Tan, HuiLv, Mengmeng Zhao, Min Wu, Jinping Zhou, Xumu Zhang*, Lina Zhang*,Highly Selective Conversion of Cellobiose and Cellulose to Hexitols by Ru-BasedHomogeneous Catalyst under Acidic Condition, Ind. Eng. Chem. Res., 2016, 55,5263-5270. 12. Cai You, Biao Wei, XiuxiuLi, Yusheng Yang, Yue Liu, Hui Lv,* and Xumu Zhang*,Rhodium-Catalyzed Desymmetrization by Hydroformylation of Cyclopentenes:Synthesis of Chiral Carbocyclic Nucleosides, Angew. Chem. Int.Ed. 2016,55, 6511-6514. 13. Xu Deng, Shao-Fei Ni,Zheng-Yu Han, Yu-Qing Guan, Hui Lv, Li Dang,* and Xu-MuZhang*, Enantioselective Rhodium-Catalyzed Cycloisomerization of(E)-1,6-Enynes, Angew. Chem. Int. Ed. 2016,55,6295-6298 14. Xuefeng Tan, Guozhen Wang,Ziyue Zhu, Conghui Ren, Jinping Zhou, Hui Lv, XiaoyongZhang, Lung Wa Chung,*Lina Zhang,* Xumu Zhang*, Hydrogenation of AldehydesCatalyzed by an Available Ruthenium Complex, Org. Lett. 2016,18, 1518-1521. 15. Wenchao Gao, Qingli Wang,Yun Xie, Hui Lv*, and Xumu Zhang*, Rhodium-catalyzedAsymmetric Hydrogenation of α-Dehydroamino Ketones: A General Approach toChiral α-amino Ketones, Chem.-asian J., 2016, 11,231-233. 16. Hailong Yang, Ningning Huo,Ping Yang, Hao Pei, Hui Lv*, Xumu Zhang*, Rhodium catalyzedasymmetric hydrogenation of 2-pyridine ketones, Org. Lett. 2015, 17,4144-4147. 17. Xuefeng Tan, Qingli Wang,Yuanhua Liu, Fangyuan Wang, Hui Lv*, Xumu Zhang*, A NewDesigned Hydrazine Group-contained Ruthenium Complex Used for CatalyticHydrogenation of Esters, Chem. Comm., 2015, 51,12193-12196. 18. Jun Jiang, Wenxin Lu, HuiLv*, Xumu Zhang*, Highly Efficient Synthesis of Chiral a-CF3Amines via Rh-Catalyzed Asymmetric Hydrogenation, Org. Lett. 2015, 17,1154-1156. 19. Jianjian Ji, Caiyou Chen,Jiayu Cai, Xinrui Wang, Kai Zhang, Liyang Shi, Hui Lv*, Xumu Zhang*, HighlyEnantioselective Synthesis of Non-natural Aliphatic a-Amino Acids viaAsymmetric Hydrogenation, Org. Biomol. Chem., 2015, 13,7624. 20. Jingjing Meng, MinGao, Hui Lv*, Xumu Zhang*, Highly EnantioselectiveHydrogenation of Ortho-Alkoxy Tetrasubstituted Catalyzed by a Rh/(R,S)-JosiPhosCatalyst, Org. Lett. 2015, 17, 1842-1845. 21. Xuefeng Tan, Yan Wang,Yuanhua Liu, Fangyuan Wang, Liyang Shi, Ka-Ho Lee, Zhenyang Lin, HuiLv*, and Xumu Zhang* Highly Efficient Tetradentate Ruthenium Catalystfor Ester Reduction: Especially for Hydrogenation of Fatty Acid Esters. Org.Lett. 2015, 17,454-457. 22. Min Gao, Jing-jingMeng, Hui Lv*, and Xumu Zhang*, Highly Regio- andEnantioselective Synthesis of g,d-Unsaturated Amido Esters by CatalyticHydrogenation of Conjugated Enamides. Angew. Chem. Int. Ed. 2015, 54,1885-1887. 23. Qingli Wang, Wenhua Huang,Haoquan Yuan, Qin Cai, Liming Chen, Hui Lv*, Xumu Zhang*,Rhodium-Catalyzed Enantioseletive Hydrogenation of Tetrasubstituted α-Acetoxyβ-Enamido Esters: a New Ap-proach to Chiral α-Hydroxyl-β-Amino Acidderivatives. J. Am. Chem. Soc. 2014, 136, 16120−16123. 24. Caiyou Chen, Pan Li, ZhoumiHu, Heng Wang, Huaisu Zhu, Xinquan Hu, Yan Wang, Hui Lv*,Xumu Zhang*, Synthesis and Application of a New Triphosphorus Ligand forRegioselective Linear Hydroformylation: A Potential Way for the Stepwise Replacementof PPh3 for Industrial Use, Org. Chem. Front. 2014, 1,947. 25. Ming Zhou, Tanglin Liu, MinCao, Zejian Xue, Hui Lv*, Xumu Zhang*, HighlyEnantioseletive Synthesis of Chiral Cyclic Allylic Amines via Rh-catalyzedAsymmetric Hydrogenation，Org. Lett. 2014，16, 3484-3487.
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发表于 2018-3-27 19:15:37
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