北京大学新材料学院刘屹东特聘研究员

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刘屹东
职       务：特聘研究员、硕导
最高学历：纽约市立大学博士
邮       箱：liuyd@pkusz.edu.cn

      1998年获北京大学化学专业理学学士和知识产权法专业法学学士，2006年获纽约市立大学化学博士。2006年至2010年在美国哥伦比亚大学医学中心任副研究员。2013年被聘为教育部、科技部“春晖杯”中国留学人员创新创业大赛评审专家。
      主要研究方向包括高性能材料、有机化学与药物化学、有机光电材料与器件。高性能材料领域主要涉及聚酰亚胺-聚苯胺半导体导电膜和抗电晕型多层聚酰亚胺复合薄膜的开发；有机化学与药物化学领域主要包含生物活性小分子的设计与合成，其中几类性能突出的化合物已经授权制药公司进行商业开发,在有机光电材料与器件领域已申请专利20余篇。

当前开展工作领域：
高性能高分子复合材料、生物医学材料、有机电子材料。

实验室：
高性能复合材料及器件实验室


代表性成果：
1. Y. Liu, R. Bittman; “Synthesis of fluorescent lactosylceramide stereoisomers”;    Chem. Phys. Lipids 142(1-2), 58-69 (2006). View
2. R.D. Singh, Y. Liu, C.L. Wheatley, E.L. Holicky, A. Makino, D.L. Marks, T. Kobayashi, G. Subramaniam, R. Bittman, R.E. Pagano;   “Caveolar Endocytosis and Microdomain Association of a Glycosphingolipid Analog Is Dependent on Its Sphingosine Stereochemistry”;    J. Biol. Chem.  281(41), 30660-30668 (2006). View
3. Y. Xie, S. Deng, C.J. Thomas, Y. Liu, Y. Zhang, A. Rinderspacher, W. Huang, G. Gong, M. Wyler, E. Cayanis, N. Aulner, U. Többen, C. Chung, S. Pampou, N. Southall, D. Vidović, S. Schürer, L. Branden, R.E. Davis, L.M. Staudt, J. Inglese, C.P. Austin, D.W. Landry, D.H. Smith, D.S. Auld; “Identification of N-(quinolin-8-yl)benzenesulfonamides as agents capable of down-regulating NFκB activity within two separate high-throughput screens of NFκB activation”; Bioorg. Med. Chem. Lett., 18(1), 329-335 (2008). View
4. Y. Xie, G. Gong, Y. Liu, S. Deng, A. Rinderspacher, L. Branden and D. W. Landry; “Convenient preparation of N-8-quinolinyl benzenesultams as novel NF-κB inhibitors”; Tetrahedron Lett., 49(14), 2320-2323 (2008). View
5. Y. Xie, Y. Liu, G. Gong, A. Rinderspacher, S. Deng, D. H. Smith, U. Többen, E. Tzilianos, L. Branden, D. Vidović, C. Chung, S. Schürer, L. Tautz, D. W. Landry; “Discovery of a novel submicromolar inhibitor of the lymphoid specific tyrosine phosphatase”; Bioorg. Med. Chem. Lett., 18(9), 2840-4 (2008). View
6. S.P. Soni, D.S. LoCascio, Y. Liu, J. A. Williams, R. Bittman, W. Stillwell, S.R. Wassall; “Docosahexaenoic Acid Enhances Segregation of Lipids between Raft and Nonraft Domains:2H-NMR Study”; Biophys. J., 95 (1), 203-214 (2008). View
7. G. Gong, Y. Xie, Y. Liu, A. Rinderspacher, S. Deng, Y. Feng, Z. Zhu, Y. Tang, M. Wyler, N. Aulner, U. Toebben, D.H. Smith, L. Branden, C. Chung, S. Schürer, D. Vidović, D.W. Landry; “Discovery of novel small molecule cell type-specific enhancers of NF-κB nuclear translocation”; Bioorg. Med. Chem. Lett., 19(4), 1191-1194 (2009). View
8. A.Rinderspacher, M.L. Cremona, Y. Liu, S. Deng, Y. Xie, G. Gong, N. Aulner, U. Tobben, K. Myers, C. Chung, M. Andersen, D. Vidovic, S. Schurer, L. Branden, A. Yamamoto, D.W. Landry; “Potent inhibitors of Huntington protein aggregation in a cell-based assay”,Bioorg. Med. Chem. Lett., 19(6), 1715-1717 (2009). View
9. Y. Xie, Y. Liu, G. Gong, D. H. Smith, F. Yan, A. Rinderspacher, Y. Feng, Z. Zhu, X. Li, S. Deng, L. Branden, D. Vidović, C. Chung, S. Schürer, C. Morisseau, B.D. Hammock, D.W. Landry; “Discovery of Potent Non-urea Inhibitors of Soluble Epoxide Hydrolase”; Bioorg. Med. Chem. Lett., 19(8), 2354-2359 (2009). View
10. Y. Xie, A. Rinderspacher, Y. Liu, G. Gong, D.H. Smith, M. Wyler, L. Branden, S. Deng; “Small-molecule modulators of the NF-κB pathway newly identified by a translocation-based cellular assay”; Curr. Top. Med. Chem., 9(13), 1172-1180 (2009).
11. N. Paragas, A. Qiu, Q. Zhang, B. Samstein, S. Deng, K.M. Schmidt-Ott, M. Viltard, W.Yu, C.S. Forster,  G. Gong, Y. Liu, R. Kulkarni, K. Mori, A. Kalandadze, A.J. Ratner, P. Devarajan, D.W. Landry, V. D’Agati, C. Lin, J. Barasch; “ The Ngal reporter mouse detects the response of the kidney to injury in real time”; Nat. Med. 17, 216-222(2011). View
12. T. Vang, Y. Xie, W. H. Liu, D. Vidović, Y. Liu, S. Wu, D. H. Smith, A. Rinderspacher, C. Chung, G.Gong, T. Mustelin, D. W. Landry, R.C. Rickert, S. Schürer, S. Deng, L. Tautz; “Inhibition of Lymphoid Tyrosine Phosphatase by Benzofuran Salicylic Acids”; J. Med. Chem.  54(2), 562-571(2011). View
13. Y. Min, Y. Yang, Y. Poojari, Y. Liu, J. Wu, D.J. Hansford, A.J. Epstein; “Sulfonated Polyaniline-based Organic Electrodes for Controlled Electrical Stimulation of Human Osteosarcoma Cells”; Biomacromolecules 14, 1727−1731(2013). View
14. S. Tong, T. Fan, W. Zeng, D. Zhang, C.-Y. Kao, Y. Liu,* Y. Min, A.J. Epstein; “Formation of tunable three-dimensional networks of graphene hydrogel via covalent bond”, Synthetic Met. 196, 27-32(2014). View
15. Y. Min, Y. Liu, Y. Poojarib, J. Wub, B.E. Hildreth III, T.J. Rosol, A.J. Epstein; “Self-doped polyaniline-based interdigitated electrodes for electrical stimulation of osteoblast cell lines”;Synthetic Met. 198, 308-313(2014). View
16. T. Fan, S. Tong, W. Zeng, Q. Niu, Y. Liu*, C.-Y. Kao, J. Liu, W. Huang, Y. Min, A.J. Epstein; “Self-assembling sulfonated graphene/polyaniline nanocomposite paper for high performance supercapacitor”, Synthetic Met. 199, 79-86(2014). View
17. T. Fan, W. Zeng, W. Tang, C. Yuan, S. Tong, K. Cai, Y. Liu*, W. Huang, Y. Min, A.J. Epstein; “Controllable size-selective method to prepare graphene quantum dots from graphene oxide”, Nanoscale Res. Lett. 10:55(2015). View
18. T. Fan, W. Zeng, Q. Niu, S. Tong, K. Cai, Y. Liu*, W. Huang, Y. Min, A.J. Epstein; “Fabrication of high-quality graphene oxide nanoscrolls and application in supercapacitor”, Nanoscale Res. Lett. 10:192(2015). View
19. T. Fan, C. Yuan, W. Tang, S. Tong, Y. Liu*, W. Huang, Y. Min, A.J. Epstein; “A Novel Method of Fabricating Flexible Transparent Conductive Large Area Graphene Film”, Chin. Phys. Lett. 32(7), 076802(2015). View