武汉大学高等研究院陈宜鸿

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陈宜鸿，武汉大学教授，特聘研究员，博士生导师台湾清华大学化学系本科毕业，2007 年获得美国Emory大学博士学位(导师: Prof. Frank E. McDonald)，以天然物合成为主要课题。然后以洪堡学者身份在慕尼黑大学(Ludwig-Maximilians-Universität)从事博士后研究(导师: Prof. Paul Knochel），之后担任慕尼黑大学研究员。长期从事金属有机领域的研究。近 5 年的研究方向集中在发展制备空气中稳定的固态有机锌试剂，与药物合成上的应用。2018年10月起担任武汉大学高等研究院特聘研究员。


特聘研究员，博士生导师
地址：湖北省武汉市武昌区八一路299号，邮编：430072
邮箱： yihuch@cup.uni-muenchen.de


研究领域:有机化学，金属有机
研究方向：金属试剂与过渡金属催化的机理研究；光电纳米催化与流动化学的研究。


代表性论文:
1. “Cobalt-Catalyzed Electrophilic Amination of Aryl- and Heteroaryl-Zinc Pivalates with NHydroxylamine Benzoates” Chen, Y.-H.; GraßlS.; Knochel, P. Angew. Chem. Int. Ed. 2018, 57, 1108.
2. “Preparation of Solid Polyfunctional Alkynylzinc Pivalates with Enhanced Air and Moisture Stability for Organic Synthesis” Chen, Y.-H.; Tüllmann, C. P.; Ellwart, M.; Knochel, P. Angew. Chem. Int. Ed. 2017, 56, 9236.
3. “Preparation and Applications of Solid, Salt Stabilized Zinc Amide Enolates with Enhanced Air and Moisture Stability” Chen, Y.-H.; Ellwart, M.; Toupalas, G.; Ebe, Y.; Knochel, P. Angew. Chem. Int. Ed. 2017, 56, 4612.
4. “Solid Organozinc Pivalates: A New Class of Zinc Organometallics with Greatly Enhanced Air- and Moisture Stability” Chen, Y.-H.; Ellwart, M.; Malakhov, V.; Knochel, P. Synthesis 2017, 49, 3215.
5. “Preparation of functionalized organoaluminiums by direct insertion of aluminium to unsaturated   halides.” Bluemke, T.; Chen, Y.-H.; Peng, Z.; Knochel, P.” Nat. Chem. 2010, 2, 313. (Equal contribution with B.T.)
6. “LiCl-mediated preparation of functionalized benzylic indium(III) halides and highly chemoselective palladium-catalyzed cross-coupling in a protic cosolvent” Chen, Y.-H.; Sun, M.; Knochel, P. Angew. Chem. Int. Ed. 2009, 48, 2236.
7. “Total Synthesis of the Sphingolipid Biosynthesis Inhibitor, Fumonisin B1.”  Pereira, C. L.; Chen, Y.-H.; McDonald, F. E. J. Am. Chem. Soc. 2009, 131, 6066.   
8. “Preparation of Aryl and Heteroaryl Indium(III) Reagents by the Direct Insertion of Indium in the Presence of LiCl.” Chen, Y.-H.; Knochel, P. Angew. Chem. Int. Ed. 2008, 47, 7648.            
9. “New Chiral Synthons for Efficient Introduction of Bispropionates via Stereospecific Oxonia-Cope Rearrangement.” Chen, Y.-H.; McDonald, F. E. J. Am. Chem. Soc. 2006, 128, 4568.