|
李炳志 现任职称/职务：教授/博士生导师
通讯地址：天津大学卫津路校区天南楼B902
电子邮箱：bzli@tju.edu.cn
办公电话：022-27402503 研究方向: 1. 合成生物学：人工基因组设计与合成、酿酒酵母五六糖利用能力及其耐受能力构建 2. 木质纤维素生物转化过程研究：预处理、高效发酵过程 3.系统生物学：微生物与胁迫环境相互作用关系 博士和硕士招生方向： 1、合成生物学 2、分子生物学 3、制药工程-生物方向 教育经历： 2005.9~2010.6：天津大学化工学院生物化工专业，获工学博士学位 2001.9~2005.6：南开大学生命科学学院生物技术专业，获理学学士学位 工作经历： 2017.01-今： 教授，天津大学化工学院。 2015.03-今: 博士生导师，天津大学化工学院。 2014.07-2016.12: 副教授，天津大学化工学院。 2014.03-今: 硕士生导师，天津大学化工学院。 2010.10-2014.06： 讲师，天津大学化工学院。 学术兼职: 国际清洁能源论坛理事（2012-） Frontiers in Bioenergy Research杂志ReviewEditor (2015-) Frontiers in Bioengineering andBiotechnology杂志Review Editor (2015-) 中国生物工程学会青年工作委员会委员（2017-） 中国化工学会生物化工专委会青年学者工作委员会副秘书长（2017-） 学术成就: 2016年获国家基金委优秀青年基金 2016年入选天津市青年科技优秀人才 2016年入选天津大学北洋学者计划 2015年获闵恩泽能源化工奖青年进步奖 2013年入选天津大学北洋学者青年骨干教师计划 科研项目: 国家基金委优秀青年基金（2017.1-2019.12） 国家基金委面上项目（2016.1-2019.12） 天津市科技计划项目（2013.10-2017.3） 国家基金委青年基金（2012.1-2014.12） 天津市自然科学基金青年基金（2012.4-2015.3） 教育部新教师基金：（2012.1-2014.12） 973课题子课题（2013.1-2017.12） 863课题子课题（2012.11-2015.12） 973课题子课题（2011.1-2012.12） 论著专利: 第一作者与通讯作者发表学术论文50余篇，申请专利20余项。 <2017年> 33. Qin L, Li X, Zhu JQ, Li WC, Xu H, GuanQM, Zhang MT,Li BZ*, Yuan YJ.Optimization of ethylenediamine pretreatment andenzymatic hydrolysis to produce fermentable sugars from corn stover. IndustrialCrops and Products. 2017 August; 102:51-57. 32. Zhang W#, Liu H#, Li X#, Liu D, DongXT, Li FF, Wang EX,Li BZ*, Yuan YJ. Production of naringenin from D-xylose withco-culture ofE. coliandS. cerevisiae. Engineering in Life Sciences. 2017. 31．Liu GG,Li BZ*, Li C,Yuan YJ. Enhancement of Simultaneous Xylose and Glucose Utilization byRegulating ZWF1 and PGI1 in Saccharomyces cerevisiae. Transactions of TianjinUniversity. 2017 May 17;23(2):201-210. 30. Liu D#,Li BZ#, Liu H, Guo XJ, Yuan YJ*.Profiling influences of gene overexpression on heterologous resveratrolproduction inSaccharomyces cerevisiae.Frontiers in Chemical Science andEngineering. 2017Mar 20; 11(1): 117-125. 29. Wu Y#,Li BZ#, Zhao M, Mitchell LA, XieZX, Lin QH, Wang X, Xiao WH, Wang Y, Zhou X, Liu H, Li X, Ding MZ, Liu D, ZhangL, Liu BL, Wu XL, Li FF, Dong XT, Jia B, Zhang WZ, Jiang GZ, Liu Y, Bai X, SongTQ, Chen Y, Zhou SJ, Zhu RY, Gao F, Kuang Z, Wang X, Shen M, Yang K,Stracquadanio G, Richardson SM, Lin Y, Wang L, Walker R, Luo Y, Ma PS, Yang H,Cai Y, Dai J, Bader JS, Boeke JD, Yuan YJ*. Bug mapping and fitness testing ofchemically synthesized chromosome X. Science. 2017Mar 10; 355(6329).pii:eaaf4706. 28. Xie ZX#,Li BZ#, Mitchell LA, Wu Y, QiX, Jin Z, Jia B, Wang X, Zeng BX, Liu HM, Wu XL, Feng Q, Zhang WZ, Liu W, DingMZ, Li X, Zhao GR, Qiao JJ, Cheng JS, Zhao M, Kuang Z, Wang X, Martin JA,Stracquadanio G, Yang K, Bai X, Zhao J, Hu ML, Lin QH, Zhang WQ, Shen MH, ChenS, Su W, Wang EX, Guo R, Zhai F, Guo XJ, Du HX, Zhu JQ, Song TQ, Dai JJ, Li FF,Jiang GZ, Han SL, Liu SY, Yu ZC, Yang XN, Chen K, Hu C, Li DS, Jia N, Liu Y,Wang LT, Wang S, Wei XT, Fu MQ, Qu LM, Xin SY, Liu T, Tian KR, Li XN, Zhang JH,Song LX, Liu JG, Lv JF, Xu H, Tao R, Wang Y, Zhang TT, Deng YX, Wang YR, Li T,Ye GX, Xu XR, Xia ZB, Zhang W, Yang SL, Liu YL, Ding WQ, Liu ZN, Zhu JQ, LiuNZ, Walker R, Luo Y, Wang Y, Shen Y, Yang H, Cai Y, Ma PS, Zhang CT, Bader JS,Boeke JD, Yuan YJ*. “Perfect” designer chromosome V and behavior of a ring derivative. Science.2017Mar 10; 355(6329). pii: eaaf4704. 27. Qin L#, Li X#, Liu L, Zhu JQ, Guan QM,Zhang MT, Li WC,Li BZ*, Yuan YJ. Dual effect of soluble materials in pretreatedlignocellulose on simultaneous saccharification and co-fermentation process forthe bioethanol production.Bioresource Technology. 2017 Jan;224:342-348. 26. Li WC#, Li X#, Qin L, Zhu JQ, Han X,LiBZ*, Yuan YJ. Reducing sugar loss in enzymatic hydrolysis of ethylenediaminepretreated corn stover.Bioresource Technology. 2017 Jan;224:405-410. <2016年> 25. Zhu JQ#, Li X#, Qin L, Li WC, Li HZ,LiBZ*, Yuan YJ. In situ detoxification of dry dilute acid pretreated corn stoverby co-culture of xylose-utilizing and inhibitor-tolerantSaccharomycescerevisiaeincreases ethanol production.Bioresource Technology. 2016Oct;218:380-7. 24. Qin L, Liu L, Li WC, Zhu JQ, Li X,LiBZ*, Yuan YJ.Inhibition of lignin-derived phenolic compounds tocellulase.Biotechnology for Biofuels.2016Mar 22;9:70. 23. Qin L, Liu L, Li WC, Zhu JQ,Li BZ*,Yuan YJ. Evaluation of soluble fraction and enzymatic residual fraction ofdilute dry acid, ethylenediamine, and steam explosion pretreated corn stover onthe enzymatic hydrolysis of cellulose.Bioresource Technology. 2016 Mar4;209:172-179. 22. Hu ML, Zha J, He LW, Lv YJ, Shen MH,Zhong C,Li BZ*, Yuan YJ. Enhanced bioconversion of cellobiose by industrialSaccharomyces cerevisiae used for cellulose utilization.Frontiers inMicrobiology. 2016 Feb 15;7:241. <2015年> 21. Qin L, Li WC, Zhu JQ, Liang JN,Li BZ*,Yuan YJ.Ethylenediamine pretreatmentchanges cellulose allomorph and ligninstructure of lignocellulose at ambient pressure.Biotechnology for Biofuels.2015 Oct 29;8:174. 20. Qi X#, Zha J#, Liu GG, Zhang W,LiBZ*,Yuan YJ. Heterologous xylose isomerase pathway and evolutionary engineeringimprove xylose utilization in Saccharomyces cerevisiae.Frontiers inMicrobiology.2015. Oct 8;6:1165. 19. Wang X, Bai X, Chen DF, Chen FZ,Li BZ*,Yuan YJ. Increasing proline and myo-inositol improves tolerance ofSaccharomycescerevisiaeto the mixture of multiple lignocellulose-derivedinhibitors.Biotechnology for Biofuels. 2015. Sep 15. 8:142. 18. Zhu JQ, Qin L, Li WC, Zhang J, Bao J,Huang YD,Li BZ*, Yuan YJ.Simultaneous saccharification and co-fermentation ofdry diluted acid pretreated corn stover at high dry matter loading: overcomingthe inhibitors by non-tolerant yeast.Bioresource Technology. 2015 Sep6;198:39-46. 17. Luo Y#,Li BZ#, Liu D#, Zhang L, Chen Y,Jia B, Zeng BX, Zhao H, Yuan YJ*. Engineered biosynthesis of natural productsin heterologous hosts.Chemical Society Reviews. 2015 Aug 7;44(15):5265-5290. 16. Qi H#,Li BZ#, Zhang WQ, Liu D, YuanYJ*. Modularization of genetic elements promotes synthetic metabolicengineering.Biotechnology Advances. 2015 Nov 15;33(7):1412-9. 15. Shen MH, Song H,Li BZ*, Yuan YJ.Deletion of D-ribulose-5-phosphate 3-epimerase (RPE1) induces simultaneousutilization of xylose and glucose in xylose-utilizingSaccharomycescerevisiae.Biotechnology Letters. 2015, 37(5):1031-1036. 14. Liu ZH#, Qin L#,Li BZ*, YuanYJ.Physical and chemical characterizations of corn stover from leadingpretreatment methods and the effects on enzymatic hydrolysis.ACS SustainableChemistry & Engineering. 2015, 3 (1):140–146. (IDS:AY3XY) <2014年> 13. Liu ZH, Qin L, Zhu JQ,Li BZ*, YuanYJ.Simultaneous saccharification and fermentation of steam-exploded corn stoverat high glucan loading and high temperature.Biotechnology forBiofuels. 2014 Dec 4; 7:167. (IDS: AZ4UW)(Highly accessed paper) 12. Zhu JQ, Qin L,Li BZ*, Yuan YJ. Simultaneoussaccharification and co-fermentation of aqueous ammonia pretreated corn stoverwith an engineered Saccharomyces cerevisiae SyBE005.Bioresource Technology.2014 Oct;169:9-18. (IDS: AN8ZH) 11. Lv YJ, Wang X, Ma Q, Bai X,Li BZ*, YuanYJ. Proteomic analysis reveals complex metabolic regulation in Saccharomycescerevisiae cells against multiple inhibitors stress.Applied Microbiology andBiotechnology. 2014 Mar;98(5):2207-21. (IDS:AB9JB) 10. Feng L, Qin L, Liu ZH, Dong CY,Li BZ*,Yuan YJ. Combined severity during pretreatment chemical and temperature on thesaccharification of wheat straw using acids and alkalis of differingstrength.BioResources. 2014, 9(1):24-38.(IDS:AB7UO) 9. Wang X, Jin M*, Balan V, Jones AD,Li Xia,Li BZ*, Dale BE, Yuan YJ. Comparative metabolic profiling revealedlimitations in xylose-fermenting yeast during co-fermentation of glucose andxylose in the presence of inhibitors.Biotechnology and Bioengineering. 2014,111:152-164. (IDS: 265VB) <2013年> 8. Qin L, Liu ZH, Jin MJ,Li BZ*, Yuan YJ.High temperature aqueous ammonia pretreatment and post-washing enhance the highsolids enzymatic hydrolysis of corn stover.Bioresource Technology.2013Oct;146:504-11.(IDS:231TZ) 7. Liu ZH, Qin L, Jin MJ, Pang F,Li BZ*,Kang Y, Dale BE,Yuan YJ.Evaluation of storage methods for the conversion ofcorn stover biomass to sugars based on steam explosionpretreatment. Bioresource Technology.2013;132:5-15.（IDS:113YZ）(曾入选ESI highlycited paper) 6. Wang X,Li BZ*, Ding MZ, Zhang WW, YuanYJ. Metabolomic analysis reveals key metabolites related to the rapidadaptation of Saccharomyce cerevisiae to multiple inhibitors of furfural,acetic acid, and phenol.OMICS. 2013 Mar;17(3):150-9.(IDS:107AC) 5. Liu ZH, Qin L, Pang F, Jin MJ,Li BZ*,Kang Y, Dale BE, Yuan YJ. Effects of biomass particle size on steam explosionpretreatment performance for improving the enzyme digestibility of cornstover.Industrial Crops and Products. 2013; 44:176-184.（IDS:099XO）(ESI highlycited paper) <2010年> 4.Li BZ, Cheng JS, Ding MZ, Yuan YJ*.Transcriptome analysis of differential responses of diploid and haploid yeastto ethanol stress.Journal of Biotechnology. 2010 Aug; 148(4):194-203. (IDS:639KA) 3.Li BZ, Yuan YJ*. Transcriptome shifts inresponse to furfural and acetic acid inSaccharomyces cerevisiae. AppliedMicrobiology and Biotechnology. 2010 May; 86(6):1915-24. (IDS: 587BD) 2.Li BZ, Cheng JS, Qiao B, Yuan YJ*.Genome-wide transcriptional analysis ofSaccharomyces cerevisiaeduringindustrial bioethanol fermentation.Journal of Industrial Microbiology andBiotechnology. 2010 Jan; 37:43-55. (IDS: 536GS) 1.Li BZ, Balan V*, Yuan YJ*, Dale BE.Process optimization to convert forage and sweet sorghum bagasse to ethanolbased on ammonia fiber expansion (AFEX) pretreatment.Bioresource Technology. 2010Feb; 101(4):1285-92. (IDS: 523KJ)
|
发表于 2018-5-8 19:41:49
QQ好友和群
QQ空间
腾讯微博
腾讯朋友
收藏
转播
分享
淘帖