华南理工大学材料学院生物医学工程系董华教授

jianchi

董华
所在系所：        生物医学工程系
职  称：        教授
研究领域：        生物微加工技术、生物芯片、生物材料等
教育部跨/新世纪优秀人才获得者
招生专业
材料学（高分子材料方向）
生物医学工程（生物医学材料与组织工程方向） 材料学（高分子材料方向）
生物医学工程（生物医学材料与组织工程方向） 材料工程
通信方式
通信地址：        广州市天河区五山路381号华南理工大学材料学院
邮政编码：        （保密）
办公地点：        大学城B12
办公电话：        （保密）
电子邮箱：        donghua@scut.edu.cn
移动电话：        （保密）


教育与工作经历
2015-                教授，华南理工大学材料科学与工程学院生物医学工程系
2012- 2014     上岗教授
2012- 2014      副教授，华南理工大学材料科学与工程学院
                           广东省”千百十工程”校级培养对象(2012)
                           华南理工大学优秀青年学者(2012)
2010-2012     副教授，华南理工大学生物科学与工程学院
                          教育部新世纪优秀人才(2011)
2008-2010     博士后，美国北卡和北卡州立大学生物医学工程系
2006-2008     留校，新加坡南洋理工大学化学与生物医学工程系
2004-2006     博士后，新加坡南洋理工大学化学与生物医学工程系
1999-2004     博士，武汉大学化学学院物理化学专业
1995-1999     本科，武汉大学化学人才基地班


科研与教学情况
回国后主要从事生物微加工、生物传感器、图案化的生物材料、生物芯片和医疗微器件的研究和开发工作，在Analytical Chemistry, Biosensors & Bioelectronics, Lab on a Chip, Journal of Materials Chemistry B等SCI杂志上发表文章40多篇，目前文章他引1500多次，参与编写英文专著1部 (“Electrochemical sensors, biosensors and their biomedical applications” Elsevier, 2008), 申请发明专利5项，获批3项。目前是国际期刊RSC Advances的顾问编委（Adversory board member），Associate editor，并受邀担任Journal of the American Chemistry Society (JACS), Electrochemical and Solid-state Letters (ESL), Journal of Applied Polymer Science (JAPS)等多个SCI杂志的审稿人。2011年获批“教育部新世纪优秀人才”,2012年入选广东省“千百十工程”校级培养对象(第七批)和第一批杰出人才培养计划(优秀青年学者)。目前主持国基面上项目，国基青年项目，教育部新世纪优秀人才，中央高校基本科研业务费（重点项目,滚动项目）,教育部留学归国人员科研启动费等基金项目，欢迎具有材料、生物和化学专业背景的研究生报考。


英文专著
>> Chang Ming Li*, Hua Dong, Qin Zhou and Kai H. Goh. Book Chapter (Chapter 11): Biochips-Fundamentals and Applications, “Electrochemical sensors, biosensors and their biomedical applications”, Elsevier, 2008，307-383 [除导师外第一作者].
SCI文章 (*=Corresponding author)
>> Huimin He, Xiaodong Cao, Hua Dong*, Ting Ma, Gregory F. Payne*, Reversible Programming of Soft Matter with Reconfigurable Mechanical Properties. Advanced Functional Materials. DOI: 10.1002/adfm.201605665.
>> Ting Ma, Xijie Gao, Hua Dong*, Huimin He, Xiaodong Cao*，High-Throughput Generation of Hyaluronic Acid Microgels via Microfluidics-Assisted Enzymatic Crosslinking and/or Diels-Alder Click Chemistry for Cell Encapsulation and Delivery. Applied Materials Today. Accepted.
>> Xiaoguang Lin, Jie Yao, Hua Dong*, Xiaodong Cao*, Effective cell/particle sorting and separation in screen-printed continuous flow microfluidic devices with 3D sidewall electrodes.  Industrial & Engineering Chemistry Research. 2016, 55, 13085−13093.
>>  Tao Hu, Qingtao Li, Hua Dong,* Wenwu Xiao, Ling Li, Xiaodong Cao*, Patterning Electrospun Nanofibers via Agarose Hydrogel Stamps to Spatially Coordinate Cell Orientation in Microfluidic Device.Small 2017, 13, 1602610.
>> Xiaodong Cao, Biyan Zhu, Tao Chen, Xufeng Zhang, Hua Dong*, Recombinant protein A immobilized on cross-linked cellulose microspheres for immunoglobulin G adsorption from human plasma.BioResources 2016, 11, 4885-4898.
>>  Yimei Fan, Xiaodong Cao*, Tao Hu, Xiaoguang Lin, Hua Dong*, Xuenong Zou, Enhancement of Enzymatic Activity Using Microfabricated Poly(ε–caprolactone)/Silica Hybrid Microspheres with Hierarchically Porous Architecture. Journal of Physical Chemistry C 2016, 120 ,3955–3963
>>  Hua Dong, Guannan Tang, Wenxiu Li, Ting Ma, Xiaodong Cao*, One-Step Fabrication of PLGA/TiO2 Hybrid Microspheres with Tunable Surface Texture for Controlled Drug Release Application. Journal of Materials Science: Materials in Medicine. 2016, 27, 7
>> Qing Zhang, Hua Dong, Yuli Li, Ye Zhu, Lei Zeng, Huichang Gao,  Bo Yuan, Xiaofeng Chen*, Chuanbin Mao*,Microgrooved polymer substrates promote collective cell migration to accelerate fracture healing in an in vitro model.ACS Applied Materials & Interfaces. 2015, 7, 23336–23345.
>> Xiaodong Cao, WenxiuLi, Ting Ma, Hua Dong*, One-step fabrication of polymeric hybrid particles with core-shell, patchy, patchy Janus and Janus architectures via microfluidic-assisted phase separation process. RSC Advances. 2015,5,79969-79975.
>> Xiaodong Cao, Biyan Zhu, Xufeng Zhang, Hua Dong*, Polymyxin B immobilized on cross-linked cellulose microspheres for endotoxin adsorption, Carbohydrate Polymers, 2016, 136, 12-18.
>> Huichang Gao, Xiaodong Cao, Hua Dong*, Xiaoling Fu, Yingjun Wang*, Influence of 3D microgrooves on C2C12 cell proliferation, migration, alignment, F-actin protein expression and gene expression.Journal of Materials Science & Technology. Accepted.
>> Qing Zhang, Yuli Li, Hao Sun, Lei Zeng, Xian Li, Bo Yuan, Chengyun Ning，Hua Dong*, Xiaofeng Chen*,hMSCs bridging across micro-patterned grooves. RSC Advances. 2015, 5, 47975-47982.
>> Huichang Gao, Hua Dong (co-first author), Xiaodong Cao, Xiaoling Fu,Ye Zhu, Chuanbin Mao*, Yingjun Wang*, Effective spatial separation of PC12 and NIH3T3 cells by the microgrooved surface of biocompatible polymer substrates. Langmuir 2015, 31, 6797-6806.
>> Wenxiu Li, Hua Dong*, Guannan Tang, Ting Ma, Xiaodong Cao*,Controllable microfluidic fabrication of Janus and microcapsule particles for drug delivery application.RSC Advances. 2015, 5, 23181-23188.
>> Guannan Tang, Wenxiu Li, Xiaodong Cao, Hua Dong*, In-Situ Microfluidic Fabrication of Multi-Shape Inorganic/Organic Hybrid Particles with Controllable Surface Texture and Porous Internal Structure.RSC Advances.2015, 5, 12872-12878.
>> Yong Su, Hongwu Zhu, Hua Dong*, A Novel Electrochemical Immunosensor Incorporating a Pyrrole/4-(3-Pyrrolyl) Butyric Acid Conducting Polymer. Analytical Letter. 2015, 48, 477-488.
>> Hongwu Zhu, Xiaoguang Lin, Yong Su, Hua Dong*, Jianhua Wu. Screen-printed microfluidic dielectrophoresis chip for cell separation. Biosensors and Bioelectronics. 2015, 63, 371-378.
>> Guohou Miao, Xiaofeng Chen*,Hua Dong, Liming Fang, Cong Mao, Yuli Li, Zhengmao Li, Qing Hu. Investigation of emulsified, acid and acid-alkali catalyzed mesoporous bioactive glass microspheres for bone regeneration and drug delivery. Materials Science and Engineering C.2013, 33,4236-4243.
>>  Zhengmao  Li; Xiaofeng Chen; Naru  Zhao , Hua Dong; Yuli Li;  Cai Lin,Stiff macro-porous bioactive glass-ceramic scaffold: Fabrication by rapid prototyping template, characterization and in vitro bioactivity Materials Chemistry and physics  2013,141,76-80.  
>>  Wanting Peng, Zhongmin Qiao, Qing Zhang, Xiaodong Cao, Xiaofeng Chen, Hua Dong*, Jingwen Liao, Chengyun Ning*. Micropatterned TiO2 nanotube: fabrication, characterization and in vitro protein/cell responses.Journal of Materials Chemistry B 2013,1, 3506-3512.
>>  Ling Yu,Shu Rui Ng, Yang Xu, Hua Dong, Yingjun Wang*, Chang Ming Li*, Advances of Lab-on-a-chip in Isolation, Detection and Post-processing of Circulating Tumour Cells. Lab on a chip 2013, 13, 3163-3182.  
>>  Xinting Zheng, Ling Yu, Yun Liu,Hua Dong, Yinjun Wang*, Peiwu Li, Chang Ming Li*, On-chip Investigation of Cell-drug Interactions.Advanced Drug Delivery Reviews. 2013，65，1556-1574.
>> Shanshan Huang, Wanting Peng, Chengyun Ning*, Qing Hu, Hua Dong*, Nanostructure Transition on Anodic Titanium: Structure Control via a Competition Strategy between Electrochemical Oxidation and Chemical Etching.Journal of Physical Chemistry C2012, 116, 22359−22364.
>> Shanshan Huang, Chengyun Ning*, Wanting Peng, Hua Dong*, Anodic formation of Ti nanorods with periodic length Electrochemistry Communications 2012, 17, 14-17.
>>  Hua Dong, Glenn M Walker*,Adjustable-Stiffness Tubes viaThermal Modulation of a Low Melting Point Polymer.Smart Materials and Structures. 2012, 21, 042001.
>>  Hua Dong, Glenn M Walker*.Adjustable stiffness films via thermal modulation. Macromolecular Materials &Engineering. 2010, 295, 735-741.
>> Hua Dong*, Xiaodong Cao, Chang Ming Li, Functionalized Polypyrrole Film: Synthesis,Characterization, and Potential Applications in Chemical and Biological Sensors. ACS Applied Materials & Interface. 2009, 1, 1599-1606.
>> Hua Dong*, Xiaodong Cao, Nanoporous gold thin film: fabrication, structure evolution, and its application as high performance anode in direct borohydride fuel cell. Journal of Physical Chemistry C 2009, 113, 603-609.
>>  Xiaodong Cao, Hua Dong, Chang Ming Li*, The Enhanced Mechanical Properties of a Covalently Bound Chitosan-Multiwalled Carbon NanotubeNanocomposite.Journal of Applied Polymer Science  2009, 113,466-472.
>> Weihua Hu, Chang Ming Li*, Hua Dong, Electrochemically polymerized poly(pyrrole-co-pyrrole propylic acid) films for covalent immobilization of high-density protein and its label-free SPR immunosensor. Analytical Chimica Acta 2008, 630, 67-74.
>> Hua Dong, Xiaodong Cao, Chang Ming Li*, Weihua Hu. An In Situ Electrochemical Surface Plasmon Resonance Immunosensor with Polypyrrole Propylic Acid Film: Comparison between SPR and Electrochemical Responses from Polymer Formation to Protein Immunosensing. Biosensors & Bioelectronics 2008, 23, 1055-1062.
>> Hua Dong, Chang-Ming Li*, Yi-Fan Zhang, Xiao-Dong Cao, Ye Gan. Screen-printed microfluidic device for electrochemical immunoassay.  Lab on a chip.  2007, 7, 1752-1758. highlighted in the RSC’s Chemical Biology Research Articles virtual journal.
>> Ruixiang Feng, Hua Dong, Yuliang Cao, Xinping Ai, Hanxi Yang, AgNi-catalyzed anode for direct borohydride fuel cells. International Journal of Hydrogen Energy. 2007, 32, 4544-4549.
>> Weiyong Yuan, Hua Dong, Chang Ming Li*, Xiao Qiang Cui, Ling Yu, Zhi-song Lu, Qin Zhou, pH-controlled construction of chitosan/alginate multilayer film: characterization and application for antibody immobilization. Langmuir. 2007, 23, 13046-13052.
>> Chang Ming Li*, Hua Dong, Xiaodong Cao, John H.T. Luong, and Xueji Zhang. Implantable Electrochemical Sensors for Biomedical and Clinical Applications: Progress, Problems, and Future Possibilities. Current Medicinal Chemistry, 2007, 14, 937-951.
>> Xiaodong Cao, Chang Ming Li,* Haifeng. Bao, Qiaoliang Bao, Hua Dong, Fabrication of strongly fluorescent quantum dot-Polymer composite in aqueous solution. Chemistry of Materials 2007, 19, 3773-3779.
>> Xiaodong Cao, Hua Dong, and Chang Ming Li*. New Nanocomposite Materials Reinforced with Flax Cellulose Nanocrystals in Waterborne Polyurethane. Biomacromolecules 2007, 8, 899-904.
>> Jianfeng Zang, Changming Li*, Xiaoqiang Cui, J.X. Wang, Xiaowei. Sun, Hua Dong, Changqin Sun: Tailoring Zinc Oxide Nanowires for High Performance Amperometric Glucose Sensor. Electroanalysis2007, 19, 1008-1014.
>> Weihua Hu, C. M. Li*, Xiaoqiang Cui, Hua Dong, Qin Zhou: In Situ Studies of Protein Adsorptions on Poly(pyrrole-co-pyrrole propylic acid) Film by Electrochem-SPR. Langmuir, 2007, 23, 2761-2767.
>> Hua Dong, Chang Ming Li,*, Wei Chen, Qin Zhou, Zhao Xian Zeng, and John H. T. Luong. Sensitive Amperometric Immunosensing Using Polypyrrolepropylic Acid Films for Biomolecule Immobilization. Analytical Chemistry 2006, 78, 7424-7431.
>> Hua Dong, Chang Ming Li∗, Qin Zhou, Jian-Bo Sun, Jian-Ming Miao. Sensitive electrochemical enzyme immunoassay microdevice based on architecture of dual ring electrodes with a sensing cavity chamber. Biosensors & Bioelectronics 2006, 22, 621–626.
>> Hua Dong, Ruixiang Feng, Xinping Ai, Yuliang Cao, Hanxi Yang,* and Chuansin Cha. Electrooxidation Mechanisms and Discharge Characteristics of Borohydride on Different Catalytic Metal Surfaces.  Journal of Physical Chemistry B 2005, 109, 10896-10901.
>> Rui-Xiang Feng, Hua Dong, Ya-Dong Wang, Xin-Ping Ai, Yu-Liang Cao, Han-Xi Yang *. A simple and high efficient direct borohydride fuel cell with MnO2-catalyzed cathode.  Electrochemistry Communications 2005, 7, 449–452.
>> Hua Dong, Xin-Ping Ai, Han-Xi Yang*.Carbon/Ba–Fe–Si alloy composite as high capacity anode materials for Li-ion batteries.  Electrochemistry Communications 2003, 5, 952–957.
>> Hua Dong, Rui-Xiang Feng, Xin-Ping Ai, Yu-Liang Cao, Han-Xi Yang∗.Structural and electrochemical characterization of Fe–Si/C composite anodes for Li-ion batteries synthesized by mechanical alloying. Electrochimica Acta2004, 49, 5217–5222.


>> Jingxian Yu, Lei Wang, Yadong Wang, Hua Dong, Hanxi Yang*, Electrochemical hydrogen storage in nanosized amorphous NixB particles. Journal of Electrochemical Society2004, 151, A1124-A1127.
>> Hua Dong, Hanxi Yang*,Xinping Ai, Chuansin Cha. Hydrogen production from catalytic hydrolysis of sodium borohydride solution using nickel boride catalyst. International Journal of Hydrogen Energy 2003, 28, 1095 – 1100.
专利：
>> 一种硅合金和碳基材料复合物的制备方法，发明专利，杨汉西 董华 艾新平，授权公告号 CN 1252846C 授权公告日：2006年4月19日
>> 过渡金属硼化物催化剂在硼氢化物水解反应制氢中的用途，发明专利， 杨汉西 董华 艾新平，授权公告号:CN 1290608C授权公告日 2006年12月20日
>> 一种氢气的制备方法及装置 发明专利 杨汉西 董华 艾新平 授权公告号:CN 1252846C授权公告日：2010年5月12日
>> Glenn M Walker, Ravish Sachar, Hua Dong, Thermally responsive composite materials. US Patent (Patent application number: 20120219744)
>>一种利用丝网印刷技术制备微流控介电泳芯片的方法 发明专利 董华 朱洪武 林晓光 苏勇 申请号：201410109289.0
主讲的课程包括 “先进材料进展”，“生物材料学导论”“医用生物材料及其仿生学”和“生物微加工和生物芯片”。