山西大学分子科学研究所阴彩霞

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阴彩霞，女，1978年4月，理学博士，山西大学分子科学研究所教授，博导。 “山西省学术技术带头人”、“山西省组织部第二批青年拔尖人才”、“山西省中青年拔尖人才”、"山西省优秀青年学术带头人"、 "山西省优秀青年科技工作者"、“太原地区青年科技拔尖人才”，山西省优秀青年基金获得者。2005年7月获得山西大学理学博士学位，2005年12月晋升为副教授。2009年10月晋升教授。2006.8-2007.8 台湾大学彭旭明院士课题组博士后研究员。2014.9-2016.8美国密苏里大学Tim E. Glass教授实验室访学。截止目前以第一作者或者通讯作者在Chem Soc Rev,J Am Chem Soc,Angew Chem Int Ed,Org Lett，Anal Chem, Chem Eur J, Biosens Bioelectron, Sci Rep, Chem Commun, Analyst，Sens Actuators B, Anal Bioanal Chem, Dyes Pigments等期刊发表学术论文100余篇，获国家发明专利授权22项。主持国家自然科学基金四项项目（No. 20081032，21072119，21472118，21775096），山西省青年科学基金（No.2009021006-2，2014021002）及山西省回国留学人员科研项目(No.200815，2012-007)，山西省留学择优基金等。荣获山西省自然科学三等奖，第一完成人。

Analytical Chemistry, Chemical Communication, Inorganic Chemistry, Biosensors and Bioelectronics, ACS Applied Materials & Interfaces, The Journal of Organic Chemistry, Crystal Growth & Design, Sensors & Actuators: B. Chemical, Sensors, Spectroscopy Letters, Academia Journal of Agricultural Research, Talanta, Analytica Chimica Acta, Dyes Pigments, Journal of Agricultural and Food Chemistry，Tetrahedron Lett., Open Journal of Inorganic Chemistry, Materials Research Bulletin, Journal of Applied Polymer Science, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, Analytical Methods, RSC Advance, The Scientific World Journal, 高等学校化学学报，分子科学学报，化学研究与应用，化学通报，有机化学，科技论文在线，International Journal of Water Resources and Environmental Engineering, sensor letters, 等国内外期刊的审稿人。

研究方向: 荧光探针及其生物传感。
联系方式：
地址：太原市坞城路92号
单位：山西大学分子科学研究所
邮编：030006
电话: 0351-7010699
eMail: yincx@sxu.edu.cn

代表性研究论文：
1. Cai-Xia Yin,* Kang-Ming Xiong,Fang-Jun Huo,J ames C. Salamanca, and Robert M. Strongin*, Fluorescent Probes with Multiple Binding Sites for the Discrimination of Cys,Hcy ,and GSH Angew.Chem. Int. Ed., 2017, 56, 13188-13198..
2. Yongkang Yue, Fangjun Huo, Peng Ning,Yongbin zhang,Jianbin Chao,Xiangming Meng,* Caixia Yin,* Dual-site Fluorescent Probe for Visualizing the Metabolism of Cys in Living Cells, J. Am. Soc. Chem., 2017, 139, 3181-3185.
3. Weijie Zhang, Tao Liu, Fangjun Huo, Peng Ning, Xiangming Meng,and Caixia Yin* ,Reversible Ratiometric Fluorescent Probe for Sensing Bisulfate/H2O2 and Its Application in Zebrafish, Anal. Chem., 2017, 89, 8079?8083.
4. Yongkang Yue, Fangjun Huo, Xiaoqi Li, Ying Wen, Tao Yi*, James Salamanca, Jorge O. Escobedo, Robert M. Strongin*, Caixia Yin*, pH-Dependent Fluorescent Probe That Can Be Tuned for Cysteine or Homocysteine, Org. Lett., 2017, 19, 82-85.
5. Caixia Yin,* Fangjun Huo, Nicholas P. Cooley, David Spencer, Kyle Bartholomew, Charles L. Barnes, Timothy E. Glass,* A Two-Input Fluorescent Logic Gate for Glutamate and Zinc, ACS Chem. Neurosci., 2017, 8, 1159?1162.
6. Ying Wen, Weijie Zhang, Tao Liu, Fangjun Huo, and Caixia Yin,* Pinpoint Diagnostic Kit for Heat Stroke by Monitoring Lysosomal pH, Anal. Chem., 2017, DOI: 10.1021/acs.analchem.7b03612
7. Yong kang Yue, Fangjun Huo, Jianbin Chao, Yongbin Zhang, Ramón Martínez-Máez,* Caixia Yin,* “Enhanced SNAr” promoted ultrafast fluorescent probe for thiophenols detection in aqueous solution and in living cells, Anal. Chem., 2016, 88, 10499?10503.
8. Yongkang Yue, Fangjun Huo, Songyi Lee, Caixia Yin,* Juyoung Yoon,*Jianbin Chao, Yongbin Zhang, Fangqin Cheng*, A Dual Colorimetric/Fluorescence System for Determining pH Based on the Nucleophilic Addition Reaction of an o-Hydroxymerocyanine Dye, Chem. Eur. J., 2016, 22, 1239-1243.
9. YutaoYang, BozanBai, MingJin, ZhidongXu, JinchaoZhang, WeiLi, WenzhiXu*, Xiang Wang, CaixiaYin*, Fluorescent imaging of Au3+ in living cells with two new high selective Au3+ probes, Biosens. Bioelectron., 2016, 86, 939–943.
10. Yutao Yang, Fangjun Huo, Caixia Yin,* Ming Xu, Ying Hu, Jianbin Chao, Yongbin Zhang, Timothy E. Glass*, Juyoung Yoon*, A novel method for the synthesis of 1,2-benzisoxazoline-3-one and its application to hypochlorite recognition, J. Mater. Chem. B, 2016, 4, 5101-5104.
11. Fangjun Huo, Jin Kang, Caixia Yin*, Jianbin Chao, Yongbin Zhang, Highly selective fluorescent and colorimetric probe for live–cell monitoring of sulphide based on bioorthogonal reaction, Sci. Rep., 5:8969，DOI: 10.1038/srep08969.
12. Yutao Yang, Caixia Yin*, Fangjun Huo, Jianbin Chao, Yongbin Zhang, Shuo Jin, Simple 1,8-diaminonaphthalene-based fluorescence chemosensor forhypochlorites and its practical application, Sens. Actuators B, 2014, 199, 226–231.
13. Caixia Yin, Fangjun Huo,* Jingjing Zhang Ramón Martínez-Máez, Yutao Yang, Haigang Lv, Sidian Li, Thiol-addition reactions and their application in thiol recognition, “Thiol-addition reactions and their application in thiol recognition, Chem. Soc. Rev., 2013, 42, 6032-6059.
14. Yutao Yang, Fangjun Huo, Caixia Yin* , Anmin Zheng, Jianbin Chao, Yingqi Li, Zongxiu Nie, Ramón Martínez-Má?ez, Diansheng Liu, Thiol-chromene click chemistry A coumarin-based derivative and its use as regenerable thiol probe and in bioimaging applications, Biosens. Bioelectron., 2013, 47, 300–306.
15. Yutao Yang, Caixia Yin,* Fangjun Huo,** Yueyin Chu, Hongbo Tong, Jianbin Chao, Fangqin Cheng, Anmin Zheng, “pH-sensitive fluorescent salicylaldehyde derivative for selective imaging of hydrogen sulfide in living cells”，Sens. Actuators B, 2013, 186, 212– 218.
16. Fangjun Huo, Caixia Yin*, Yutao Yang, Jianbin Chao, Diansheng Liu, Ultraviolet-Visible Light (UV-Vis)-Reversible but Fluorescence- Irreversible Chemosensor for Copper in Water and Its Application in Living Cells, Anal. Chem, 2012, 84, 2219?2223
17.. Fangjun Huo, Yutao Yang，Jing Su, Yuanqiang Sun, Caixia Yin*, Xuxiu Yan, Indicator approach to develop a chemosensor for the colorimetric sensing of thiol-containing in water and its application for the thiol detection in plasma, Analyst, 2011, 136, 1892-1897.
18. Fangjun Huo, Yuanqiang Sun, Jing Su, Yutao Yang, Caixia Yin,* Jianbin Chao, Chromene “Lock”, Thiol “Key” and Mercury(II) ion “Hand”: A Single Molecular Machine Recognition System, Org lett, 2010, 12, 4756-4759.
19.. Fangjun Huo, Yuanqiang Sun, Jing Su, Jianbin Chao, Haijuan Zhi, Caixia Yin, Colorimetric detection of thiols using a chromene molecule, Org. Lett., 2009, 11, 4918-4921.
20. Caixia Yin, Gin-Chen Huang, Ching-Kuo Kuo, Ming-Dung Fu, Hao-Cheng Lu, Jhih-hong Ke, Kai-Neng Shih,Yi-Lin Huang, Gene-Hsiang Lee, Chen-Yu Yeh, Chun-Hsien Chen, Shie-Ming Peng. Extended Metal-Atom Chains with an Inert Second Row Transition Metal: [Ru5(μ5-tpda)4X2] (tpda2- = tripyridyldiamido dianion, X = Cl and NCS). J. Am. Soc. Chem., 2008, 130, 10090-10092.
21. Caixia Yin, Fangjun Huo, Pin Yang, UV-Vis spectroscopic study directly detecting inorganic phosphorus in urine and our reagent kit, Anal. Bioanal. Chem., 2006, 384, 774-779.
22. Caixia Yin, Fangjun Huo, Pin Yang, An ion-based chromogenic detecting method for phosphate-containing derivatives in physiological condition. Sens, Actuators B, 2005, 109, 291-299.
23．Caixia Yin, Fei Gao, Fang-Jun Huo, Pin Yang, Applying Yb3+ Ion as a Simple and Sensitive Probe to Detect Phosphate-contaning Derivatives in Aqueous Solution. Chem. Commun., 2004, 934-935.

国家发明专利：
1. 阴彩霞 霍方俊， 一种三结合位点试剂及其在二价铜离子检测中的应用，专利号：ZL201410194012.2， 授权日期：2016.3.30.
2. 阴彩霞 霍方俊，一种荧光检测二价铜离子的方法，专利号：ZL201310042739.4，授权日期：2015.1.28.
3. 阴彩霞 杨瑜涛 霍方俊, 一种检测硫离子的方法，专利号：ZL201310234201.3, 授权日期：2015.1.28.
4. 阴彩霞 霍方俊 杨瑜涛，一种检测半胱氨酸的试剂和方法，专利号：ZL201410033092.3，授权日期：2015.6.3.
5. 阴彩霞 杨瑜涛 霍方俊，一种检测三价金离子的方法，专利号：ZL201310041320.7，授权日期：2015.5.13.
6. 阴彩霞 霍方俊 孙远强，一种检测汞离子的方法和试剂盒，专利号：ZL201110008847.0，授权日期：2013.1.23。
7. 阴彩霞 霍方俊 杨瑜涛，一种试剂及其在检测二价铜离子中的应用，专利号：ZL201110264432.X，授权日期：2013.11.20。
8. 阴彩霞 霍方俊 孙远强，快速检测水溶液中无机磷的方法, 专利号：ZL200910073643.8，授权日期：2011.1.5
9. 阴彩霞 孙远强 霍方俊 刘艳玲，一种检测水溶液中草酸根的方法，ZL200810054882.4，授权日期， 2010.3.17。
10. 阴彩霞 杨频 霍方俊, 一种目视检测尿液中无机磷的方法及其试剂盒，专利号：ZL200510012445.2，授权日期：2007.5.23。
11. 阴彩霞 杨频 霍方俊一种检测血液中磷酸根的方法，专利号：ZL200410088432.9. 授权日期：2007.1.17。