研究方向
多尺度分子模拟；
DNA分子机器和反应网络；
Energy landscape方法及其在生物物理体系中的应用
近年代表性工作
[1] X Zhou#, D. Yao#, W. Hua, N. Huang, X. Chen, L. Li*, M. He, Y. Zhang, Y Guo, S. Xiao*, F., Bian*, and H. Liang*; Programming colloidal bonding using DNA strand-displacement circuitry, PNAS 2020, 117, 5617-5623.
[2] S Xiao, D Sharpe, D Chakraborty, D Wales*; Energy Landscapes and Hybridization Pathways for DNA Hexamer Duplexes, J. Phys. Chem. Lett. 2019, 10, 6771-6779.
[3] S Xiao, H Liang*, D Wales*; The Contribution of Backbone Electrostatic Repulsion to DNA Mechanical Properties is Length-Scale-Dependent, J. Phys. Chem. Lett. 2019, 10, 4829-4835.
[4] X Sun, B Wei, Y Guo, S Xiao*, X Li, D Yao, X Yin, S Liu, H Liang*; A Scalable “Junction Substrate” to Engineer Robust DNA Circuits, J. Am. Chem. Soc. 2018, 140 (31), 9979–9985.
[5] L Chen, X Li, Y Zhang, T Chen, S Xiao* and HJ Liang*; Morphological and mechanical determinants of cellular uptake of deformable nanoparticles, Nanoscale 2018, 10, 11969-11979.