北京大学化学与分子工程学院樊新元

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樊新元，北京大学化学与分子工程学院副研究员。研究兴趣集中在生物正交化学反应、光催化等“遥控化学生物学工具”的开发与应用研究，实现了蛋白质快速激活、药物靶向释放、受体配体相互作用原位调控等技术突破。近5年的研究成果以(共)通讯/第一作者发表在包括J. Am. Chem. Soc., Angew. Chem. Int. Ed., Nat. Commun., Acc. Chem. Res., J. Catal.等国际知名学术期刊。主持国家自然科学基金重大研究计划培育、面上等多项基金，以骨干参与科技部重点研发计划专项项目及北京市基金委重点基金等项目。




SELECTED PUBLICATIONS
(1) Fan, X.*; Gong, X.#; Ma, M.#; Wang, R.; Walsh, P. J.* “Visible Light-Promoted CO2 Fixation with Imines to Synthesize Diaryl α-Amino Acids”, Nat. Comm.2018, DOI: 10.1038/s41467-018-07351-2.
(2) Wang, R.; Ma, M.; Gong, X.; Fan, X.*; Walsh, P. J.* “Reductive Cross-Coupling of Aldehydes and Imines Mediated by Visible Light Photoredox Catalysis”, Org. Lett.2018, DOI: 10.1021/acs.orglett.8b03394.
(3) Wang, R.; Ma, M.; Gong, X.; Fan, X.*; Walsh, P. J.* “Visible Light-Mediated Umpolung Reactivity of Imines: Ketimine Reductions with Cy2NMe and Water”, Org. Lett.2018, 2433.
(4) Fan, X.; Walsh, P. J.* “Chelation-Controlled Additions to Chiral α- and β-Silyloxy, α-Halo, and β-Vinyl Carbonyl Compounds”, Acc. Chem. Res.2017, 50, 2389.
(5) Fan, X.; Li, J.; Chen, P.* “Bioorthogonal Chemistry in Living Animals”, Natl. Sci. Rev.2017, 4, 300.
(6) Fan, X.; Ge, Y.; Lin, F.; Yang, Y.; Zhang, G.; Ngai, W.; Lin, Z.; Zheng, S.; Wang, J.; Zhao, J.; Li, J.; Chen, P.* “Optimized Tetrazine Derivatives for Rapid Bioorthogonal Decaging in Living Cells”, Angew. Chem. Int. Ed.2016, 55, 14046.
(7) Ge, Y.#; Fan, X.#; Chen, P.* “A genetically encoded multifunctional unnatural amino acid for versatile protein manipulations in living cells”, Chem. Sci.2016, 7, 7055. (# Co-first author).
(8) Fan, X.; Rodríguez-Escrich, C.; Wang, S.; Sayalero, S.; Pericàs, M. A.* “Highly Enantioselective Cross-Aldol Reactions of Acetaldehyde Mediated by a Dual Catalytic System Operating under Site Isolation”, Chem. Eur. J.2014, 20, 13089.
(9) Fan, X.; Rodríguez-Escrich, C.; Sayalero, S.; Pericàs, M. A.* “Paraldehyde as an Acetaldehyde Precursor in Asymmetric Michael Reactions Promoted by Site-Isolated Incompatible Catalysts”, Chem. Eur. J.2013, 19, 10814.
(10) Fan, X.; Sayalero, S.; Pericàs, M. A.* “Asymmetric α-Amination of Aldehydes Catalyzed by PS-Diphenylprolinol Silyl Ethers: Remediation of Catalyst Deactivation for Continuous Flow Operation”, Adv. Synth. Catal.2012, 354, 2971.